Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli
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The Alzheimer's amyloid-degrading peptidase, neprilysin: can we control it?The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. Identification of novel substrates for the Kell proteinNeprilysin inhibition to treat heart failure: a tale of science, serendipity, and second chancesHigh concentration of carboxypeptidase M in lungs: presence of the enzyme in alveolar type I cellsIs there a tripeptidyl peptidase in the renal brush-border membrane?Proteins of the kidney microvillar membrane. The 130 kDa protein in pig kidney, recognized by monoclonal antibody GK5C1, is an ectoenzyme with aminopeptidase activityProteolysis controls endogenous substance P levelsA three-dimensional model of the neprilysin 2 active site based on the X-ray structure of neprilysin. Identification of residues involved in substrate hydrolysis and inhibitor binding of neprilysin 2Cell-specific activity of neprilysin 2 isoforms and enzymic specificity compared with neprilysinInvestigation of the metabolism of substance P at the blood-brain barrier using capillary electrophoresis with laser-induced fluorescence detection.Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts.The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function.Neuronal localization of the neutral endopeptidase 'enkephalinase' in rat brain revealed by lesions and autoradiography.Effects of tachykinins on uterine smooth muscle.Active site mutations change the cleavage specificity of neprilysin.Proteins of the kidney microvillar membrane. Purification and properties of carboxypeptidase P from pig kidneys.Neutral endopeptidase and kininase II mediate glucocorticoid inhibition of neurogenic inflammation in the rat trachea.Peptidase modulation of the pulmonary effects of tachykinins in tracheal superfused guinea pig lungs.Neutral endopeptidase-like enzyme controls the contractile activity of substance P in guinea pig lungTachykinins and tachykinin receptors in human uterus.Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance PToluene diisocyanate increases airway responsiveness to substance P and decreases airway neutral endopeptidase.Distinct subcellular patterns of neprilysin protein and activity in the brains of Alzheimer's disease patients, transgenic mice and cultured human neuronal cells.Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?Dual roles of substance P: modulator of immune and neuroendocrine functions.Neuropeptides: metabolism to bioactive fragments and the pharmacology of their receptors.Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer's disease.Proctolin degradation by membrane peptidases from nervous tissues of the desert locust (Schistocerca gregaria)Role of endopeptidase-24.11 in the inactivation of atrial natriuretic peptide.Hydrolysis of substance P in the presence of the osteosarcoma cell line SaOS-2: release of free amino acids.The impact of amyloid precursor protein signalling and histone deacetylase inhibition on neprilysin expression in human prostate cells.A Group of Weakly Bound to Neurons Extracellular Metallopeptidases (NEMPs).Neutral endopeptidase expression in mesangial cells.Tachykinin peptides, receptors, and peptidases in airway disease.Internalization and degradation of peptides of the bombesin family in Swiss 3T3 cells occurs without ligand-induced receptor down-regulation.Interactions between neutral endopeptidase (EC 3.4.24.11) and the substance P (NK1) receptor expressed in mammalian cells.Involvement of enzymatic degradation in the inactivation of tachykinin neurotransmitters in neonatal rat spinal cord.Interaction of mammalian neprilysin with binding protein and calnexin in Schizosaccharomyces pombe.Identification of membrane dipeptidase as a major glycosyl-phosphatidylinositol-anchored protein of the pancreatic zymogen granule membrane, and evidence for its release by phospholipase A.Characterization of neutral endopeptidase 24.11 in dog glomeruli.
P2860
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P2860
Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1983
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Substance P and [Leu]enkephali ...... peptidase of kidney microvilli
@en
Substance P and [Leu]enkephali ...... eptidase of kidney microvilli.
@nl
type
label
Substance P and [Leu]enkephali ...... peptidase of kidney microvilli
@en
Substance P and [Leu]enkephali ...... eptidase of kidney microvilli.
@nl
prefLabel
Substance P and [Leu]enkephali ...... peptidase of kidney microvilli
@en
Substance P and [Leu]enkephali ...... eptidase of kidney microvilli.
@nl
P2093
P2860
P356
P1476
Substance P and [Leu]enkephali ...... peptidase of kidney microvilli
@en
P2093
P2860
P304
P356
10.1073/PNAS.80.10.3111
P407
P577
1983-05-01T00:00:00Z