about
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO geneMutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in miceDefects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31Overexpression of Fto leads to increased food intake and results in obesityNew mutations at the imprinted Gnas cluster show gene dosage effects of Gsα in postnatal growth and implicate XLαs in bone and fat metabolism but not in suckling.From mice to humans.Comprehensive Energy Balance Measurements in Mice.Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscleDisruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety.Novel phenotypes identified by plasma biochemical screening in the mouse.A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.A missense mutation in the non-neural G-protein alpha-subunit isoforms modulates susceptibility to obesity.A genetic modifier suggests that endurance exercise exacerbates Huntington's disease.Embryonic myosin is a regeneration marker to monitor utrophin based therapies for DMDMicro-utrophin Improves Cardiac and Skeletal Muscle Function of Severely Affected D2/ Mice
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description
British molecular biologist
@en
bióloga molecular británica
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name
Lee Moir
@ast
Lee Moir
@ca
Lee Moir
@en
Lee Moir
@es
Lee Moir
@fr
Lee Moir
@nl
Lee Moir
@sl
type
label
Lee Moir
@ast
Lee Moir
@ca
Lee Moir
@en
Lee Moir
@es
Lee Moir
@fr
Lee Moir
@nl
Lee Moir
@sl
prefLabel
Lee Moir
@ast
Lee Moir
@ca
Lee Moir
@en
Lee Moir
@es
Lee Moir
@fr
Lee Moir
@nl
Lee Moir
@sl
P2002
P21
P31
P496
0000-0003-4829-3597