A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene - Test2 - elhamkhani - TriplyDB

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene

http://www.wikidata.org/entity/Q28475923

about

Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons Five years of GWAS discovery Role of FTO in Adipocyte Development and Function: Recent Insights Obesity genetics in mouse and human: back and forth, and back again RNA epigenetics In utero programming of later adiposity: the role of fetal growth restriction The complex interplay of genetic and lifestyle risk factors in type 2 diabetes: an overview Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation Quantification of private information leakage from phenotype-genotype data: linking attacks Loss of FTO antagonises Wnt signaling and leads to developmental defects associated with ciliopathies Adult onset global loss of the fto gene alters body composition and metabolism in the mouse Modify or die?--RNA modification defects in metazoans A preliminary association study of fat mass and obesity associated gene polymorphisms and degenerative disc disease in a Chinese Han population Inhibition of 2-oxoglutarate dependent oxygenases A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects Routes for breaching and protecting genetic privacy WikiGWA: an open platform for collecting and using genome-wide association results The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women Intervention, integration and translation in obesity research: Genetic, developmental and metaorganismal approaches.FTO levels affect RNA modification and the transcriptome Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors.Changes in gene expression associated with FTO overexpression in mice.Genetic variation at the FTO locus influences RBL2 gene expression.Complex Relationship between Obesity and the Fat Mass and Obesity Locus From monogenic to polygenic obesity: recent advances.The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice.Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.Impact of metabolic regulators on the expression of the obesity associated genes FTO and NAMPT in human preadipocytes and adipocytes Genome wide association study identifies KCNMA1 contributing to human obesity The genetics of obesity: FTO leads the way.Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway The fat mass and obesity associated gene, FTO, is also associated with osteoporosis phenotypes FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting.

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A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene

http://www.wikidata.org/entity/Q28475923

description

2009 nî lūn-bûn

@nan

2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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JOURNAL.PGEN.1000599

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A mouse model for the metaboli ...... nd obesity associated FTO gene

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Angela Lee

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Chris Church

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Frances M Ashcroft

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James S McTaggart

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Mohamed M Quwailid

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Robert Deacon

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Sheena Lee

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Thomas Gerken

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P2860

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

Decarboxylation of alpha-ketoglutarate coupled to collagen proline hydroxylase

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity.

Genome-wide atlas of gene expression in the adult mouse brain

Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity

Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation

Inactivation of the Fto gene protects from obesity

Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure

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10.1371/JOURNAL.PGEN.1000599

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Christopher J. Schofield

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Jasmin Mecinovic

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2009-08-14T00:00:00Z

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26741820

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19680540

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2719869

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