The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
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The genetics and neuropathology of Alzheimer's diseaseAmyloid beta: multiple mechanisms of toxicity and only some protective effects?Amyloid PET in clinical practice: Its place in the multidimensional space of Alzheimer's diseaseGenetic variants in Alzheimer disease - molecular and brain network approachesAPOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.Dendritic spine pathology in neuropsychiatric disordersTranscriptomics of cortical gray matter thickness decline during normal agingAlzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans.Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.An exploratory study on CLU, CR1 and PICALM and Parkinson diseaseChoroidal Proteins Involved in Cerebrospinal Fluid Production may be Potential Drug Targets for Alzheimer's Disease Therapy.Pharmacodynamic, pharmacokinetic and pharmacogenetic aspects of drugs used in the treatment of Alzheimer's disease.Octodon degus: a strong attractor for Alzheimer research.Function and comorbidities of apolipoprotein e in Alzheimer's disease.Impaired regulation of synaptic actin cytoskeleton in Alzheimer's disease.Increased Cerebrospinal Fluid Production as a Possible Mechanism Underlying Caffeine's Protective Effect against Alzheimer's DiseaseGenomic Copy Number Analysis in Alzheimer's Disease and Mild Cognitive Impairment: An ADNI StudyThe effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype.Alzheimer's disease: pathological mechanisms and recent insights.Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites.Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals.Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk.Rapid estradiol modulation of neuronal connectivity and its implications for disease.Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression.Panel of Genetic Variations as a Potential Non-invasive Biomarker for Early Diagnosis of Alzheimer's Disease.Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging InitiativeAn Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.Multilocus genetic profiling to empower drug trials and predict brain atrophy.Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disordersThe effect of the top 20 Alzheimer disease risk genes on gray-matter density and FDG PET brain metabolism.Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration.The multiscale backbone of the human phenotype network based on biological pathwaysGenome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration.Epigenetic studies in Alzheimer's disease: current findings, caveats, and considerations for future studies.Physical Activity: A Viable Way to Reduce the Risks of Mild Cognitive Impairment, Alzheimer's Disease, and Vascular Dementia in Older Adults.Advances and perspectives from genetic research: development of biological markers in Alzheimer's disease.The concept of FDG-PET endophenotype in Alzheimer's disease.Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges.Membrane trafficking pathways in Alzheimer's disease.The role of clusterin in Alzheimer's disease: pathways, pathogenesis, and therapy.
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The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 January 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
@en
The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
@nl
type
label
The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
@en
The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
@nl
prefLabel
The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
@en
The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
@nl
P50
P1433
P1476
The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.
@en
P2093
Lars Bertram
Marc Cruts
P356
10.1016/J.TIG.2009.12.004
P577
2010-01-18T00:00:00Z