PAPP-A: a promising therapeutic target for healthy longevity. - Test2 - elhamkhani - TriplyDB

PAPP-A: a promising therapeutic target for healthy longevity.

PAPP-A: a promising therapeutic target for healthy longevity.

http://www.wikidata.org/entity/Q37678178

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One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology High-throughput serum proteomics for the identification of protein biomarkers of mortality in older men.EWS-FLI-1 creates a cell surface microenvironment conducive to IGF signaling by inducing pappalysin-1.Similarity and Variation in the Insulin-like Growth Factor 2 - H19 Locus in Primates.

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P2860

PAPP-A: a promising therapeutic target for healthy longevity.

http://www.wikidata.org/entity/Q37678178

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 29 December 2016

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

PAPP-A: a promising therapeutic target for healthy longevity.

@en

PAPP-A: a promising therapeutic target for healthy longevity.

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type

label

PAPP-A: a promising therapeutic target for healthy longevity.

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PAPP-A: a promising therapeutic target for healthy longevity.

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prefLabel

PAPP-A: a promising therapeutic target for healthy longevity.

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PAPP-A: a promising therapeutic target for healthy longevity.

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PAPP-A: a promising therapeutic target for healthy longevity

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Cheryl A Conover

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Creative Commons Attribution

P2860

The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A

A novel neutralizing antibody targeting pregnancy-associated plasma protein-a inhibits ovarian cancer growth and ascites accumulation in patient mouse tumorgrafts

Interventions for age-related diseases: Shifting the paradigm

Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin

Cyclooxygenase inhibition and atherothrombosis

Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity

Structural, gene expression, and functional analysis of the fugu (Takifugu rubripes) insulin-like growth factor binding protein-4 gene.

Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding.

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity

In vivo analysis of gene expression in long-lived mice lacking the pregnancy-associated plasma protein A (PappA) gene

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205-209

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scholarly article

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10.1111/ACEL.12564

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2

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2016-12-29T00:00:00Z

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pregnancy proteins

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5334524

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