Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
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Epigenetic modulators, modifiers and mediators in cancer aetiology and progressionNew answers to old questions from genome-wide maps of DNA methylation in hematopoietic cellsConnections between TET proteins and aberrant DNA modification in cancerThe TET2 interactors and their links to hematological malignanciesRecursive splicing in long vertebrate genes.TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes.TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancerEpigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic RegulationMathematical modeling reveals differential effects of erythropoietin on proliferation and lineage commitment of human hematopoietic progenitors in early erythroid culture.DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cellsMolecular mechanisms and clinical applications of miR-22 in regulating malignant progression in human cancer (Review).The mechanistic role of DNA methylation in myeloid leukemogenesis.New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.CMML: Clinical and molecular aspects.Epigenetics: A primer for clinicians.Stable 5-Hydroxymethylcytosine (5hmC) Acquisition Marks Gene Activation During Chondrogenic Differentiation.Epigenetic regulation of human adipose-derived stem cells differentiation.TET family dioxygenases and DNA demethylation in stem cells and cancers.Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes.A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence.Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiationChanges of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells.Cytosine 5-hydroxymethylation regulates VHL gene expression in renal clear cell carcinoma.Tet-mediated DNA hydroxymethylation regulates retinal neurogenesis by modulating cell-extrinsic signaling pathways.Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.UBE2O remodels the proteome during terminal erythroid differentiation.Hypermethylated LTR retrotransposon exhibits enhancer activity.Distinct roles for TET family proteins in regulating human erythropoiesis.Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.Survey and evaluation of mutations in the human KLF1 transcription unit.Abnormal folate metabolism causes age-, sex- and parent-of-origin-specific haematological defects in mice
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P2860
Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hydroxymethylation at gene reg ...... mitment during erythropoiesis.
@en
Hydroxymethylation at gene reg ...... mitment during erythropoiesis.
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type
label
Hydroxymethylation at gene reg ...... mitment during erythropoiesis.
@en
Hydroxymethylation at gene reg ...... mitment during erythropoiesis.
@nl
prefLabel
Hydroxymethylation at gene reg ...... mitment during erythropoiesis.
@en
Hydroxymethylation at gene reg ...... mitment during erythropoiesis.
@nl
P2093
P2860
P1433
P1476
Hydroxymethylation at gene reg ...... mitment during erythropoiesis.
@en
P2093
Alan H Shih
Alexis Rodriguez
Amit Verma
Amittha Wickrema
Aparna Vasanthakumar
Brigitte Raumann
Bruce T Lahn
Don Lavelle
Donne Bennett D Caces
P2860
P304
P356
10.1016/J.CELREP.2013.11.044
P577
2013-12-27T00:00:00Z