O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.
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Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguaninePreclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and ValidationActive and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base bindingReduction of BCNU toxicity to lung cells by high-level expression of O(6)-methylguanine-DNA methyltransferase.The role of surrogate markers in the clinical development of antiretroviral therapy: a model for early evaluation of targeted cancer drugs.Cytoplasmic sequestration of an O6-methylguanine-DNA methyltransferase enhancer binding protein in DNA repair-deficient human cellsMGMT: a personal perspective.Molecular status of pituitary carcinoma and atypical adenoma that contributes the effectiveness of temozolomide.An O6-methylguanine-DNA methyltransferase-like protein from Thermus thermophilus interacts with a nucleotide excision repair protein.Affinity purification and characterization of human O6-alkylguanine-DNA alkyltransferase complexed with BCNU-treated, synthetic oligonucleotide.Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma.Evaluation of the drug sensitivity and expression of 16 drug resistance-related genes in canine histiocytic sarcoma cell lines.Quantification of DNA interstrand crosslinks induced by ACNU in NIH/3T3 and L1210 cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.Potentiation of temozolomide and BCNU cytotoxicity by O(6)-benzylguanine: a comparative study in vitro.Bcl-2 overexpression decreases BCNU sensitivity of a human glioblastoma line through enhancement of catalase activity.Amplification of the DNA repair gene O6-methylguanine-DNA methyltransferase associated with resistance to alkylating drugs in a mammalian cell line.Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O-Alkylguanine-DNA Alkyltransferase Activity.Repair of O6-alkylguanines in the nuclear DNA of human lymphocytes and leukaemic cells: analysis at the single-cell levelAn intronic genetic variation of affects enhancer activity and is associated with glioma susceptibility
P2860
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P2860
O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
O6-Alkylguanine-DNA alkyltrans ...... bdomyosarcoma xenografts to 1-
@nl
O6-Alkylguanine-DNA alkyltrans ...... thylcyclohexyl)-1-nitrosourea.
@en
type
label
O6-Alkylguanine-DNA alkyltrans ...... bdomyosarcoma xenografts to 1-
@nl
O6-Alkylguanine-DNA alkyltrans ...... thylcyclohexyl)-1-nitrosourea.
@en
prefLabel
O6-Alkylguanine-DNA alkyltrans ...... bdomyosarcoma xenografts to 1-
@nl
O6-Alkylguanine-DNA alkyltrans ...... thylcyclohexyl)-1-nitrosourea.
@en
P2093
P2860
P356
P1476
O6-Alkylguanine-DNA alkyltrans ...... thylcyclohexyl)-1-nitrosourea.
@en
P2093
J A Houghton
P J Houghton
P2860
P304
P356
10.1073/PNAS.82.9.2985
P407
P577
1985-05-01T00:00:00Z