SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
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Human sulfatase 1 exerts anti-tumor activity by inhibiting the AKT/ CDK4 signaling pathway in melanoma.Targeting Tyrosine Phosphatases: Time to End the Stigma.Therapeutic Targeting of Oncogenic Tyrosine Phosphatases.Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases.Cytotoxic activity of Shp2 inhibitor fumosorinone in human cancer cells.Hyperglycaemia-induced methylglyoxal accumulation potentiates VEGF resistance of diabetic monocytes through the aberrant activation of tyrosine phosphatase SHP-2/SRC kinase signalling axisStructural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition
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SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 September 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
@en
SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
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type
label
SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
@en
SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
@nl
prefLabel
SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
@en
SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
@nl
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SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
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Jingwu Xie
Jinmin Miao
Lifan Zeng
Ruo-Yu Zhang
Sheng Zhang
Yunpeng Bai
Zhi-Hong Yu
Zhong-Yin Zhang
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P304
73817-73829
P356
10.18632/ONCOTARGET.12074
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P577
2016-09-16T00:00:00Z