Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases.
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Spatiotemporal regulation of Src and its substrates at invadosomesDistal loop flexibility of a regulatory domain modulates dynamics and activity of C-terminal SRC kinase (csk)Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains.Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate.C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.Mapping of p140Cap phosphorylation sites: the EPLYA and EGLYA motifs have a key role in tyrosine phosphorylation and Csk binding, and are substrates of the Abl kinase.Fulvestrant-induced cell death and proteasomal degradation of estrogen receptor α protein in MCF-7 cells require the CSK c-Src tyrosine kinase.Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.Aberrant regulation and function of Src family tyrosine kinases: their potential contributions to glutamate-induced neurotoxicity.Src family kinases and their role in hematological malignancies.Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine.C-terminal Src kinase (Csk) regulates the tricellular junction protein Gliotactin independent of Src.Network-based identification of feedback modules that control RhoA activity and cell migration.Csk-homologous kinase (Chk/Matk): a molecular policeman suppressing cancer formation and progression
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P2860
Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Structural elements and allost ...... ibition of Src-family kinases.
@en
Structural elements and allost ...... ibition of Src-family kinases.
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type
label
Structural elements and allost ...... ibition of Src-family kinases.
@en
Structural elements and allost ...... ibition of Src-family kinases.
@nl
prefLabel
Structural elements and allost ...... ibition of Src-family kinases.
@en
Structural elements and allost ...... ibition of Src-family kinases.
@nl
P2093
P2860
P1476
Structural elements and allost ...... ibition of Src-family kinases.
@en
P2093
Boonyarin Jarasrassamee
Khai-Chew Chan
Mohammed I Hossain
Ryan D Mills
P2860
P304
P356
10.3109/08977194.2010.484424
P577
2010-10-01T00:00:00Z