about
Disruption of Fyn SH3 domain interaction with a proline-rich motif in liver kinase B1 results in activation of AMP-activated protein kinaseTyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of LckBruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding proteinA phosphotyrosine displacement mechanism for activation of Src by PTPalphaSubstrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptorMitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signalingIdentification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein XTrafficking of Lyn through the Golgi caveolin involves the charged residues on alphaE and alphaI helices in the kinase domainThe unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate docking protein 1Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1Src kinase activation by direct interaction with the integrin beta cytoplasmic domainSubdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylationThe role of protein-tyrosine phosphatase 1B in integrin signalingRegulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibitionStructure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseasesCrosstalk between Src and major vault protein in epidermal growth factor-dependent cell signallingUnc119, a novel activator of Lck/Fyn, is essential for T cell activationMechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segmentActivation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sitesStructural basis for the recognition of c-Src by its inactivator CskStructure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide.The tyrosine kinase Csk dimerizes through Its SH3 domainRACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cellsAllosteric activation of the protein kinase PDK1 with low molecular weight compoundsRegulation of Sos activity by intramolecular interactions.The RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activationThe second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigmaThe crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition.Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate.Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activationRegulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin APositive and negative regulation of T-cell activation through kinases and phosphatasesIntramolecular interactions regulate SAP97 binding to GKAPThe PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activityRetroviral oncogenes: a historical primerHighly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocyclesThe chemical biology of protein phosphorylationFyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1Identification of the binding site for Gqalpha on its effector Bruton's tyrosine kinase
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Crystal structure of the Src family tyrosine kinase Hck
@ast
Crystal structure of the Src family tyrosine kinase Hck
@en
Crystal structure of the Src family tyrosine kinase Hck
@nl
type
label
Crystal structure of the Src family tyrosine kinase Hck
@ast
Crystal structure of the Src family tyrosine kinase Hck
@en
Crystal structure of the Src family tyrosine kinase Hck
@nl
prefLabel
Crystal structure of the Src family tyrosine kinase Hck
@ast
Crystal structure of the Src family tyrosine kinase Hck
@en
Crystal structure of the Src family tyrosine kinase Hck
@nl
P2093
P3181
P356
P1433
P1476
Crystal structure of the Src family tyrosine kinase Hck
@en
P2093
P2888
P3181
P356
10.1038/385602A0
P407
P577
1997-02-13T00:00:00Z
P6179
1034217411