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Monosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradationTargeting Cancer Metabolism - Revisiting the Warburg EffectsCentral role of neutrophil in the pathogenesis of severe acute pancreatitisThe two faces of miR-29Targeting Mcl-1 for the therapy of cancerInterference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma HerpesvirusesAlternative Treatments For Melanoma: Targeting BCL-2 Family Members to De-Bulk and Kill Cancer Stem CellsRegulation of Mcl-1 by SRSF1 and SRSF5 in cancer cellsModulation of Mcl-1 expression reduces age-related cochlear degenerationAge-related changes in the ratio of Mcl-1/Bax expression in the rat cochlea.Energy metabolism regulated by HDAC inhibitor attenuates cardiac injury in hemorrhagic rat model.MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies.MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells.A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinibThe Concerted Action of Mitochondrial Dynamics and Positioning: New Characters in Cancer Onset and Progression.Enhancement of X-ray Induced Apoptosis by Mobile Phone-Like Radio-Frequency Electromagnetic Fields in Mouse Spermatocyte-Derived Cells.Anti-apoptotic effects of osteopontin through the up-regulation of Mcl-1 in gastrointestinal stromal tumors.Mcl-1 ubiquitination: unique regulation of an essential survival protein.Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.Bcl-2 family proteins are involved in the signal crosstalk between endoplasmic reticulum stress and mitochondrial dysfunction in tumor chemotherapy resistance.Sorafenib: complexities of Raf-dependent and Raf-independent signaling are now unveiled.Genetic variants of NOXA and MCL1 modify the risk of HPV16-associated squamous cell carcinoma of the head and neck.Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1.Overexpression of Mcl-1L splice variant is associated with poor prognosis and chemoresistance in oral cancers.Silence of MCL-1 upstream signaling by shRNA abrogates multiple myeloma growth.Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells.Anti-apoptotic activity and proteasome-mediated degradation of Xenopus Mcl-1 protein in egg extracts.Myeloid cell leukemia-1 is associated with tumor progression by inhibiting apoptosis and enhancing angiogenesis in colorectal cancer.MCL-1ES induces MCL-1L-dependent BAX- and BAK-independent mitochondrial apoptosis.Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation.The essential role of evasion from cell death in cancer.Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation.Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-xL strategies through Mcl-1 down-regulation.Antiproliferative effect of chrysin on anaplastic thyroid cancerIL-32γ delays spontaneous apoptosis of human neutrophils through MCL-1, regulated primarily by the p38 MAPK pathway.Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance?Transcriptomic profiles of aging in purified human immune cellsCdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 June 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mcl-1; the molecular regulation of protein function.
@en
Mcl-1; the molecular regulation of protein function.
@nl
type
label
Mcl-1; the molecular regulation of protein function.
@en
Mcl-1; the molecular regulation of protein function.
@nl
prefLabel
Mcl-1; the molecular regulation of protein function.
@en
Mcl-1; the molecular regulation of protein function.
@nl
P2093
P1433
P1476
Mcl-1; the molecular regulation of protein function.
@en
P2093
Connie Lam
Luke W Thomas
Steven W Edwards
P304
P356
10.1016/J.FEBSLET.2010.05.061
P407
P577
2010-06-11T00:00:00Z