Fragile X syndrome and model organisms: identifying potential routes of therapeutic intervention.
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Networking in autism: leveraging genetic, biomarker and model system findings in the search for new treatmentsFragile X mental retardation protein is required for programmed cell death and clearance of developmentally-transient peptidergic neurons.GABA-B Agonist Baclofen Normalizes Auditory-Evoked Neural Oscillations and Behavioral Deficits in the Fmr1 Knockout Mouse Model of Fragile X Syndrome.A cell-based fascin bioassay identifies compounds with potential anti-metastasis or cognition-enhancing functions.Drosophila modeling of heritable neurodevelopmental disordersPDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndromeTherapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond.In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylationSynaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities.RNA-binding protein misregulation in microsatellite expansion disordersUsing Drosophila as a tool to identify Pharmacological Therapies for Fragile X SyndromeLithium treatment alleviates impaired cognition in a mouse model of fragile X syndrome.Involvement of Rho-family GTPases in axon branching.Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function.
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Fragile X syndrome and model organisms: identifying potential routes of therapeutic intervention.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 August 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Fragile X syndrome and model o ...... s of therapeutic intervention.
@en
Fragile X syndrome and model o ...... s of therapeutic intervention.
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type
label
Fragile X syndrome and model o ...... s of therapeutic intervention.
@en
Fragile X syndrome and model o ...... s of therapeutic intervention.
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prefLabel
Fragile X syndrome and model o ...... s of therapeutic intervention.
@en
Fragile X syndrome and model o ...... s of therapeutic intervention.
@nl
P2860
P356
P1476
Fragile X syndrome and model o ...... s of therapeutic intervention.
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P2093
Balpreet Bhogal
Thomas A Jongens
P2860
P304
P356
10.1242/DMM.002006
P577
2010-08-03T00:00:00Z