Beyond ATM: the protein kinase landscape of the DNA damage response.
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Autophagic degradation of peroxisomes in mammalsATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorNot All DDRs Are Created Equal: Non-Canonical DNA Damage ResponsesMicroRNA and signal transduction pathways in tumor radiation responseSurface Reengineering of RPA70N Enables Cocrystallization with an Inhibitor of the Replication Protein A Interaction Motif of ATR Interacting ProteinCdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress.Systemic DNA damage responses in aging and diseasesRole of RUNX2 in Breast CarcinogenesisATM, ATR and DNA-PKcs expressions correlate to adverse clinical outcomes in epithelial ovarian cancersChallenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activityMass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cellsMutant TP53 posttranslational modifications: challenges and opportunities.DNA-PK and P38 MAPK: A Kinase Collusion in Alzheimer's Disease?Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistanceRegulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition.Stress-induced DNA damage: a case study in diffuse large B-cell lymphoma.A transcriptome analysis suggests apoptosis-related signaling pathways in hemocytes of Spodoptera litura after parasitization by Microplitis bicoloratusATM release at resected double-strand breaks provides heterochromatin reconstitution to facilitate homologous recombination.ATM gene mutations in sporadic breast cancer patients from Brazil.Insect inhibitor-of-apoptosis (IAP) proteins are negatively regulated by signal-induced N-terminal degrons absent within viral IAP proteins.The COP9 signalosome is vital for timely repair of DNA double-strand breaks.Compound Library Screening Identified Cardiac Glycoside Digitoxin as an Effective Growth Inhibitor of Gefitinib-Resistant Non-Small Cell Lung Cancer via Downregulation of α-Tubulin and Inhibition of Microtubule Formation.Bridging the gap between in vitro and in vivo: Dose and schedule predictions for the ATR inhibitor AZD6738Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression.Changes in leukocyte gene expression profiles induced by antineoplastic chemotherapy.The conserved C terminus of Claspin interacts with Rad9 and promotes rapid activation of Chk1.MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cellsMolecular genetic response to varied wavelengths of light in Xiphophorus maculatus skinRegulatory mechanisms and clinical perspectives of miRNA in tumor radiosensitivity.Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence.p53 centrosomal localization diagnoses ataxia-telangiectasia homozygotes and heterozygotes.An autonomous chromatin/DNA-PK mechanism for localized DNA damage signaling in mammalian cells.Induced pluripotent stem cells from ataxia-telangiectasia recapitulate the cellular phenotype.Compensation, crosstalk and sequestering: the currency of checkpoints in cancerATM kinase inhibition preferentially sensitizes p53-mutant glioma to ionizing radiationMaternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cellsATM mediates pRB function to control DNMT1 protein stability and DNA methylation.Radiation-induced gene signature predicts pathologic complete response to neoadjuvant chemotherapy in breast cancer patients
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Beyond ATM: the protein kinase landscape of the DNA damage response.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 May 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Beyond ATM: the protein kinase landscape of the DNA damage response.
@en
Beyond ATM: the protein kinase landscape of the DNA damage response.
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type
label
Beyond ATM: the protein kinase landscape of the DNA damage response.
@en
Beyond ATM: the protein kinase landscape of the DNA damage response.
@nl
prefLabel
Beyond ATM: the protein kinase landscape of the DNA damage response.
@en
Beyond ATM: the protein kinase landscape of the DNA damage response.
@nl
P2860
P1433
P1476
Beyond ATM: the protein kinase landscape of the DNA damage response.
@en
P2093
Ariel Bensimon
Yosef Shiloh
P2860
P304
P356
10.1016/J.FEBSLET.2011.05.013
P407
P577
2011-05-08T00:00:00Z