MRK, a mixed lineage kinase-related molecule that plays a role in gamma-radiation-induced cell cycle arrest
about
The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathwayRadioresistance of Brain TumorsComplete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNAActivation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation.Mixed-lineage kinase control of JNK and p38 MAPK pathways.Phosphorylation and stabilization of topoisomerase IIα protein by p38γ mitogen-activated protein kinase sensitize breast cancer cells to its poisons.p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of doxorubicin.The MLK-related kinase (MRK) is a novel RhoC effector that mediates lysophosphatidic acid (LPA)-stimulated tumor cell invasionG protein regulation of MAPK networks.BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling.A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response.Beyond ATM: the protein kinase landscape of the DNA damage response.Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients.Role of a DNA damage checkpoint pathway in ionizing radiation-induced glioblastoma cell migration and invasion.Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling.Doxorubicin induces ZAKα overexpression with a subsequent enhancement of apoptosis and attenuation of survivability in human osteosarcoma cells.Recessive mutations in the kinase ZAK cause a congenital myopathy with fibre type disproportion.Transient global cerebral ischemia induces up-regulation of MLTKα in hippocampal CA1 neurons.Mixed lineage kinase ZAK promotes epithelial-mesenchymal transition in cancer progression.The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer.
P2860
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P2860
MRK, a mixed lineage kinase-related molecule that plays a role in gamma-radiation-induced cell cycle arrest
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2002 թվականի ապրիլին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@ast
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@en
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@en-gb
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@nl
type
label
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@ast
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@en
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@en-gb
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@nl
prefLabel
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@ast
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@en
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@en-gb
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@nl
P2093
P2860
P3181
P356
P1476
MRK, a mixed lineage kinase-re ...... tion-induced cell cycle arrest
@en
P2093
Eleanore A Gross
Linda Waldbaum
Marinella G Callow
Rosamaria Ruggieri
Suzanne Thomas
P2860
P304
P3181
P356
10.1074/JBC.M111994200
P407
P577
2002-04-19T00:00:00Z