Biogenesis of spliceosomal small nuclear ribonucleoproteins.
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Single molecule fluorescence approaches shed light on intracellular RNAsStructural basis for dual roles of Aar2p in U5 snRNP assemblyGemin5 Binds to the Survival Motor Neuron mRNA to Regulate SMN ExpressionCrystal structure and RNA-binding properties of an Hfq homolog from the deep-branching Aquificae: conservation of the lateral RNA-binding mode.Archaeal and eukaryotic homologs of Hfq: A structural and evolutionary perspective on Sm function.Small nuclear RNAs and mRNAs: linking RNA processing and transport to spinal muscular atrophy.Spinal Muscular Atrophy: From Defective Chaperoning of snRNP Assembly to Neuromuscular Dysfunction.Quality control of assembly-defective U1 snRNAs by decapping and 5'-to-3' exonucleolytic digestion.Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control.Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.Cutting, dicing, healing and sealing: the molecular surgery of tRNASplicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins.Alternative RNA splicing and cancerDisease mechanisms and therapeutic approaches in spinal muscular atrophy.Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organizationNUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins.Spatial regulation of cytoplasmic snRNP assembly at the cellular level.A U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchangeLsm proteins and Hfq: Life at the 3' endDevelopmental arrest of Drosophila survival motor neuron (Smn) mutants accounts for differences in expression of minor intron-containing genes.U1A regulates 3' processing of the survival motor neuron mRNA.A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies.The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA.Spliceosomal small nuclear ribonucleoprotein biogenesis defects and motor neuron selectivity in spinal muscular atrophy.Gem depletion: amyotrophic lateral sclerosis and spinal muscular atrophy crossover.SMN control of RNP assembly: from post-transcriptional gene regulation to motor neuron disease.Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art.mRNA metabolism and neuronal disease.UsnRNP biogenesis: mechanisms and regulation.A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy.Hypo- and Hyper-Assembly Diseases of RNA-Protein Complexes.Cajal bodies and snRNPs - friends with benefits.Diverse role of survival motor neuron protein.RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP.SMA-causing missense mutations in survival motor neuron (Smn) display a wide range of phenotypes when modeled in Drosophila.Characterization and in vivo functional analysis of the Schizosaccharomyces pombe ICLN gene.Transcriptomic comparison of Drosophila snRNP biogenesis mutants reveals mutant-specific changes in pre-mRNA processing: implications for spinal muscular atrophy.The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization.Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation.
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Biogenesis of spliceosomal small nuclear ribonucleoproteins.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Biogenesis of spliceosomal small nuclear ribonucleoproteins.
@en
Biogenesis of spliceosomal small nuclear ribonucleoproteins.
@nl
type
label
Biogenesis of spliceosomal small nuclear ribonucleoproteins.
@en
Biogenesis of spliceosomal small nuclear ribonucleoproteins.
@nl
prefLabel
Biogenesis of spliceosomal small nuclear ribonucleoproteins.
@en
Biogenesis of spliceosomal small nuclear ribonucleoproteins.
@nl
P2860
P356
P1476
Biogenesis of spliceosomal small nuclear ribonucleoproteins.
@en
P2093
Ashwin Chari
Clemens Englbrecht
P2860
P304
P356
10.1002/WRNA.87
P50
P577
2011-04-25T00:00:00Z