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Chemo-Immunotherapeutic Antimalarials Targeting Isoprenoid BiosynthesisIsoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum.Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box.Mechanistic binding insights for 1-deoxy-D-Xylulose-5-Phosphate synthase, the enzyme catalyzing the first reaction of isoprenoid biosynthesis in the malaria-causing protists, Plasmodium falciparum and Plasmodium vivax.Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS.Sterol Composition and Biosynthetic Genes of Vitrella brassicaformis, a Recently Discovered Chromerid: Comparison to Chromera velia and Phylogenetic Relationship with Apicomplexan Parasites.Mechanistic Studies of 1-Deoxy-D-Xylulose-5-Phosphate Synthase from Deinococcus radiodurans.
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description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
The isoprenoid-precursor dependence of Plasmodium spp.
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type
label
The isoprenoid-precursor dependence of Plasmodium spp.
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prefLabel
The isoprenoid-precursor dependence of Plasmodium spp.
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P2860
P356
P1476
The isoprenoid-precursor dependence of Plasmodium spp
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P2093
Jan-Ytzen van der Meer
P2860
P304
P356
10.1039/C2NP20013A
P577
2012-05-04T00:00:00Z