Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.
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Cholinergic modulation of the medial prefrontal cortex: the role of nicotinic receptors in attention and regulation of neuronal activityVarenicline Effects on Smoking, Cognition, and Psychiatric Symptoms in Schizophrenia: A Double-Blind Randomized TrialNegative affective states and cognitive impairments in nicotine dependenceMaximizing the effect of an α7 nicotinic receptor PAM in a mouse model of schizophrenia-like sensory inhibition deficits.Effects of the nicotinic α7 receptor partial agonist GTS-21 on NMDA-glutamatergic receptor related deficits in sensorimotor gating and recognition memory in ratsUnderstanding the role α7 nicotinic receptors play in dopamine efflux in nucleus accumbensEvaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia.Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.Crystallization scale purification of α7 nicotinic acetylcholine receptor from mammalian cells using a BacMam expression systemStoichiometry for activation of neuronal α7 nicotinic receptors.Human brain imaging of α7 nAChR with [(18)F]ASEM: a new PET radiotracer for neuropsychiatry and determination of drug occupancyGoing up in smoke? A review of nAChRs-based treatment strategies for improving cognition in schizophrenia.Development of [(18)F]ASEM, a specific radiotracer for quantification of the α7-nAChR with positron-emission tomographyPET tracers for imaging brain α7 nicotinic receptors: an update.Understanding the Bases of Function and Modulation of α7 Nicotinic Receptors: Implications for Drug Discovery.[(125)I]Iodo-ASEM, a specific in vivo radioligand for α7-nAChR.Influence of disulfide connectivity on structure and bioactivity of α-conotoxin TxIA.Anabaseine analogues as modulators of nicotinic acetylcholine receptor.Insights into nicotinic receptor signaling in nicotine addiction: Implications for prevention and treatment.Derivatives of dibenzothiophene for positron emission tomography imaging of α7-nicotinic acetylcholine receptors.Integration of inhibitory and excitatory effects of α7 nicotinic acetylcholine receptor activation in the prelimbic cortex regulates network activity and plasticity.Editorial: Brain cholinergic mechanisms.Research tool: Validation of floxed α7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches.PET Brain imaging of α7-nAChR with [18F]ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia.BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.Current Concepts and Treatments of Schizophrenia
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P2860
Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.
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article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.
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type
label
Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.
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prefLabel
Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.
@en
P2860
P1476
Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.
@en
P2093
Daniel Bertrand
Tanya L Wallace
P2860
P304
P356
10.1517/14728222.2013.736498
P407
P577
2012-12-11T00:00:00Z