Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.

Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.

Item
http://www.wikidata.org/entity/Q38077992
In vivo administration of a JAK3 inhibitor to chronically siv infected rhesus macaques leads to NK cell depletion associated with transient modest increase in viral loads.Novel hinge-binding motifs for Janus kinase 3 inhibitors: a comprehensive structure-activity relationship study on tofacitinib bioisosteres.Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer.Anaplastic lymphoma kinase inhibitors as anticancer therapeutics: a patent review.Selective JAK inhibitors.Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1.Signal transducer and activator of transcription 5 is implicated in disease activity in adult and juvenile onset systemic lupus erythematosus.Enhancing specificity in the Janus kinases: a study on the thienopyridine JAK2 selective mechanism combined molecular dynamics simulation.A unique case of refractory primary mediastinal B-cell lymphoma with JAK3 mutation and the role for targeted therapy.Design and synthesis of tricyclic JAK3 inhibitors with picomolar affinities as novel molecular probes.Highly selective Janus kinase 3 inhibitors based on a pyrrolo[2,3-d]pyrimidine scaffold: evaluation of WO2013085802.Dual inhibitors of Janus kinase 2 and 3 (JAK2/3): designing by pharmacophore- and docking-based virtual screening approach.Discriminating phenotypic signatures identified for tocilizumab, adalimumab, and tofacitinib monotherapy and their combinations with methotrexate.
P2860

Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.

Item
http://www.wikidata.org/entity/Q38077992
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.
@en
type
label
Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.
@en
prefLabel
Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.
@en
P2093
P2860
P304
P31
P356
10.1517/13543776.2013.765862
P407
P433
P478
P577
P698