Animal models and therapeutic prospects for Charcot-Marie-Tooth disease. - Test2 - elhamkhani - TriplyDB

Animal models and therapeutic prospects for Charcot-Marie-Tooth disease.

Animal models and therapeutic prospects for Charcot-Marie-Tooth disease.

http://www.wikidata.org/entity/Q38126454

about

Late onset neuropathy with spontaneous clinical remission in mice lacking the POZ domain of the transcription factor Myc-interacting zinc finger protein 1 (Miz1) in Schwann cells Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology.Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy.Glutamate signals through mGluR2 to control Schwann cell differentiation and proliferation Genetics of Charcot-Marie-Tooth (CMT) Disease within the Frame of the Human Genome Project Success.Therapeutic options in Charcot-Marie-Tooth diseases.Muscle spindle alterations precede onset of sensorimotor deficits in Charcot-Marie-Tooth type 2E.Schwann cell Miz without POZ: degeneration meets regeneration.PMP22 messenger RNA levels in skin biopsies: testing the effectiveness of a Charcot-Marie-Tooth 1A biomarker.Decreased ceramide underlies mitochondrial dysfunction in Charcot-Marie-Tooth 2F.Structure, function, and regulation of mitofusin-2 in health and disease.Locomotor and skeletal muscle abnormalities in trembler J neuropathic mice.CSF-1-activated macrophages are target-directed and essential mediators of Schwann cell dedifferentiation and dysfunction in Cx32-deficient mice.

P2860

Q34958666-E0AECB9A-CADA-4B18-A417-FDB85F1EEAE0 Q35821176-1BC6A23B-2FDC-4470-A0F4-DFDC238E1182 Q36866166-BD9119C4-64D8-4159-8A85-A5DB4B39821E Q37104972-973273EC-6D96-4D51-84BA-FC61A355730D Q38202508-11E19E63-8688-436B-830D-BC861FE5C978 Q38363677-CB72D5AA-B5E1-4298-BE94-5252B19B5E17 Q39374909-CC7B532F-C484-41F1-AE80-45F1022A4EEF Q43154378-CB231570-85C3-4337-A3BF-D1B34EFDCA5E Q45222726-00E74AB4-95CE-4429-A8B5-09830353011F Q47407341-0F58D3FD-D9E6-45FF-8042-79BE266BDB67 Q47606530-4CA3E23D-EB2F-4E3F-9DE9-42D1ACFD490C Q47612399-2360A246-7DBD-4A5F-9B04-137A653AEDB4 Q50604436-62CE3FF6-FEA6-4593-9DEA-6E084C1177BE

P2860

Animal models and therapeutic prospects for Charcot-Marie-Tooth disease.

http://www.wikidata.org/entity/Q38126454

description

article científic

@ca

article scientifique

@fr

articol științific

@ro

articolo scientifico

@it

artigo científico

@gl

artigo científico

@pt

artigo científico

@pt-br

artikel ilmiah

@id

artikull shkencor

@sq

artículo científico

@es

name

Animal models and therapeutic prospects for Charcot-Marie-Tooth disease.

@en

type

label

Animal models and therapeutic prospects for Charcot-Marie-Tooth disease.

@en

prefLabel

Animal models and therapeutic prospects for Charcot-Marie-Tooth disease.

@en

P1433

Q38126454-6357EAEA-ACC4-4FEE-8427-55261810AE81

P1476

Q38126454-37CCFD59-38E0-4ACA-AA85-D5F09DC5E565

P2093

Q38126454-2C5BD4CB-8705-4763-AD07-6DA0806E8502

Q38126454-4E063B22-F564-4EC6-BB2D-85C973A7A431

P2860

Q38126454-00584124-9240-43CC-BB6F-0464A774C106

Q38126454-01A578FE-314B-49F2-B174-2B8419A87EC8

Q38126454-0BD80772-A6E9-4C76-8CC0-A510706B260C

Q38126454-109239E7-824C-4838-8759-6123DDF6C783

Q38126454-10F7660B-A6ED-46BD-8FCC-5DEFCDEB1298

Q38126454-156B61E2-7677-4343-97D2-417812011B2E

Q38126454-1864AB83-D3BE-457D-B1C9-A1AAAD916EE7

Q38126454-1D63150B-0F6B-4F16-A071-3BA08370775A

Q38126454-1EF2DD4E-F488-44DF-B4FE-C6083E77F357

Q38126454-22797174-E84E-4126-89F9-D04C5C8CE497

P304

Q38126454-3D2819C9-188A-44D9-9121-D0621BF61035

P31

Q38126454-9709ED58-0A18-49B7-AD45-B542DE9A7E0E

P356

Q38126454-C87A8C39-4392-4DC0-A3D0-1B829E3BD06A

P433

Q38126454-B7E4AE84-8C2A-40E8-B2A4-E384FCA067C2

P478

Q38126454-CFA54102-BC76-47CA-BF34-7728C815B404

P577

Q38126454-65CC94A7-84C6-46BA-8B57-7679CD146D6C

P5875

Q38126454-7B902234-FF79-4527-8E97-F355F0BD022A

P698

Q38126454-CAA08967-7DCD-47F3-893D-5FB19E946F03

P356

P1433

Annals of Neurology

P1476

Animal models and therapeutic prospects for Charcot-Marie-Tooth disease.

@en

P2093

Delphine Bouhy

http://www.w3.org/2001/XMLSchema#string

Vincent Timmerman

http://www.w3.org/2001/XMLSchema#string

P2860

GDAP1, the protein causing Charcot-Marie-Tooth disease type 4A, is expressed in neurons and is associated with mitochondria

Charcot-Marie-Tooth disease type 2E, a disorder of the cytoskeleton

Deletion of the serine 34 codon from the major peripheral myelin protein P0 gene in Charcot-Marie-Tooth disease type 1B

Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy

Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments

Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations

Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy

Population frequencies of inherited neuromuscular diseases--a world survey

Peripheral neuropathies caused by mutations in the myelin protein zero

A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

P304

391-396

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/ANA.23987

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

74

http://www.w3.org/2001/XMLSchema#string

P577

2013-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

255177613

http://www.w3.org/2001/XMLSchema#string

P698

23913540

http://www.w3.org/2001/XMLSchema#string