Drug discovery and human African trypanosomiasis: a disease less neglected? - Test2 - elhamkhani - TriplyDB

Drug discovery and human African trypanosomiasis: a disease less neglected?

Drug discovery and human African trypanosomiasis: a disease less neglected?

http://www.wikidata.org/entity/Q38154344

about

Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment.Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth In Vitro and In Vivo Investigation of the Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates.Fluorinated Sterols Are Suicide Inhibitors of Ergosterol Biosynthesis and Growth in Trypanosoma brucei.Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity Foreword. Trypanosomatid disease drug discovery and target identification.Phenolic Constituents of Medicinal Plants with Activity against Trypanosoma brucei.Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.Focus on PAINS: false friends in the quest for selective anti-protozoal lead structures from Nature?

P2860

Q34297640-AAB168C7-0C89-4614-B92E-F1751C937DC7 Q35014260-D3E28C59-95DB-4FA5-8DC3-C7A1E66EA2CD Q35782846-DBD37073-B709-4EEE-90EF-474C3913E8B7 Q36219533-A5FD2F82-6496-4878-94C9-EEF81600C3ED Q36263511-89226B3A-9E9D-4A78-971B-4737901947CD Q39329032-0E2924DE-65DF-4172-BC8D-FA87559B06EA Q39498814-072F6480-7582-45D1-95A1-FBBCEBF65BC8 Q46338517-5EA3C5DF-4E4D-4AA7-9EE3-509F5B5FFB33 Q58856163-17817424-C1A0-4031-839C-FF0B3F84B18B

P2860

Drug discovery and human African trypanosomiasis: a disease less neglected?

http://www.wikidata.org/entity/Q38154344

description

article científic

@ca

article scientifique

@fr

articol științific

@ro

articolo scientifico

@it

artigo científico

@gl

artigo científico

@pt

artigo científico

@pt-br

artikel ilmiah

@id

artikull shkencor

@sq

artículo científico

@es

name

Drug discovery and human African trypanosomiasis: a disease less neglected?

@en

type

label

Drug discovery and human African trypanosomiasis: a disease less neglected?

@en

prefLabel

Drug discovery and human African trypanosomiasis: a disease less neglected?

@en

P1433

Q38154344-5956EEEE-5F13-49DF-A2E0-02548F59A712

P1476

Q38154344-5A611878-A6C7-487B-92B1-4EFB3084A2CA

P2093

Q38154344-029BED8E-510D-4345-B2E8-DA053425C74E

Q38154344-E836AEA2-74B4-49C2-803D-96ED04F77430

P2860

Q38154344-01E627D0-4B91-41F3-BC7A-65D25CA00B46

Q38154344-0679852D-7110-48D2-BB98-351CD9F743C9

Q38154344-07A3F630-65F7-4EE0-A788-6817AEC9411E

Q38154344-08132398-4EC0-4F41-B04F-9D864C6544A6

Q38154344-0B4C63F3-248A-41E4-9DB3-AC0A92EDDDDA

Q38154344-10D7CDCF-27D7-4DE9-B77D-253C0829C4FF

Q38154344-15405D19-D14A-4779-B9FD-26913503AB14

Q38154344-178EB309-3B45-4CFF-878F-D23645FE4EA7

Q38154344-1F1E5D09-CB48-4DDA-AC25-6B77A58347E1

Q38154344-257B7BBC-DAFB-4870-9C4E-957028ADED93

P304

Q38154344-5D3EF3B6-DDE8-4909-B5AC-5B5DB83C4558

P31

Q38154344-F8A489C6-E5E4-4D83-8A67-0A95342A97C7

P356

Q38154344-434D711D-793E-4562-9BF1-E861B9CE476C

P433

Q38154344-B85555BF-FA1D-4427-B874-556134EA1674

P478

Q38154344-5A592B64-29EE-4529-9C98-6AF94029B0E3

P50

Q38154344-42B04C14-0338-483F-AFC6-B9134BD5585C

P577

Q38154344-E1DBC3EC-9B88-4CC6-82DF-5C34265943E1

P5875

Q38154344-10F0FEFC-A319-49F6-B393-96DE108E431C

P698

Q38154344-0828B2C3-3502-4024-8CA7-788E65DC58C5

P921

Q38154344-10C4C713-0FAA-4415-A778-50A3B51E0A19

Q38154344-D924896B-C99B-4A8B-9D05-3AB764CD4FA2

Q38154344-F2448D53-5516-4864-931F-B913A7C2C434

P356

P1433

Future Medicinal Chemistry

P1476

Drug discovery and human African trypanosomiasis: a disease less neglected?

@en

P2093

Jonathan B Baell

http://www.w3.org/2001/XMLSchema#string

Raphaël Rahmani

http://www.w3.org/2001/XMLSchema#string

P2860

SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

Bromopyrrole alkaloids as lead compounds against protozoan parasites

Identification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatB

Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography

Discovery of Novel Trypanosoma brucei Phosphodiesterase B1 Inhibitors by Virtual Screening against the Unliganded TbrPDEB1 Crystal Structure

Structure-guided design of a selective BCL-X(L) inhibitor

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

2,4-Diaminopyrimidines as potent inhibitors of Trypanosoma brucei and identification of molecular targets by a chemical proteomics approach

P304

1801-1841

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4155/FMC.13.162

http://www.w3.org/2001/XMLSchema#string

P433

15

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

258063101

http://www.w3.org/2001/XMLSchema#string

P698

24144414

http://www.w3.org/2001/XMLSchema#string

P921

African trypanosomiasis

trypanosomiasis

(RS)-eflornithine