G-protein-coupled receptors, Hedgehog signaling and primary cilia.
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The Roles of NDR Protein Kinases in Hippo SignallingCilia in autophagy and cancerSpecialized Cilia in Mammalian Sensory SystemsMKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition ZoneApplications of phototransformable fluorescent proteins for tracking the dynamics of cellular componentsEarly eukaryotic origins for cilia-associated bioactive peptide-amidating activity.DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide.Smoothened Regulation: A Tale of Two Signals.Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells.Functional Divergence in the Role of N-Linked Glycosylation in Smoothened SignalingProteomics of Primary Cilia by Proximity LabelingDiversifying Selection Between Pure-Breed and Free-Breeding Dogs Inferred from Genome-Wide SNP AnalysisPrimary cilia found on HeLa and other cancer cellsCilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics.KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.Small tubules, surprising discoveries: from efferent ductules in the turkey to the discovery that estrogen receptor alpha is essential for fertility in the maleIntraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.Regulation of the oncoprotein Smoothened by small molecules.Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction.Primary cilia are present on human blood and bone marrow cells and mediate Hedgehog signaling.The primary cilium as a cellular receiver: organizing ciliary GPCR signalingDisruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis.Primary Cilia and Coordination of Receptor Tyrosine Kinase (RTK) and Transforming Growth Factor β (TGF-β) Signaling.Motile and non-motile cilia in human pathology: from function to phenotypes.Primary Cilia and Mammalian Hedgehog Signaling.From inflammation to gastric cancer - the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases.Using Primary Neurosphere Cultures to Study Primary Cilia.Targeting Class I Histone Deacetylases by the Novel Small Molecule Inhibitor 4SC-202 Blocks Oncogenic Hedgehog-GLI Signaling and Overcomes Smoothened Inhibitor Resistance.Activation of SMOCiliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium.The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner.TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms.Contributions of Noncanonical Smoothened Signaling During Embryonic Development.Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.The IFT-A complex recruits TULP3TULP3 is required for GPR161 localization in the cilium
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G-protein-coupled receptors, Hedgehog signaling and primary cilia.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
G-protein-coupled receptors, Hedgehog signaling and primary cilia.
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type
label
G-protein-coupled receptors, Hedgehog signaling and primary cilia.
@en
prefLabel
G-protein-coupled receptors, Hedgehog signaling and primary cilia.
@en
P2860
P1476
G-protein-coupled receptors, Hedgehog signaling and primary cilia.
@en
P2093
Rajat Rohatgi
P2860
P356
10.1016/J.SEMCDB.2014.05.002
P577
2014-05-17T00:00:00Z