Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
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DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegansAxon injury induced endoplasmic reticulum stress and neurodegenerationTwo for the Price of One: A Neuroprotective Chaperone Kit within NAD Synthase Protein NMNAT2Death Receptor 6 Promotes Wallerian Degeneration in Peripheral Axons.Immune Escape via a Transient Gene Expression Program Enables Productive Replication of a Latent Pathogen.NMNAT: It's an NAD+ synthase… It's a chaperone… It's a neuroprotector.TMEM184b Promotes Axon Degeneration and Neuromuscular Junction Maintenance.NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation.Reactive oxygen species induce neurite degeneration before induction of cell death.MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.Toll-like receptor pathway evolution in deuterostomes.Molecular mechanisms in the initiation phase of Wallerian degeneration.Axon degeneration: context defines distinct pathways.Common and Divergent Mechanisms in Developmental Neuronal Remodeling and Dying Back Neurodegeneration.Is Axonal Degeneration a Key Early Event in Parkinson's Disease?Implications of cellular models of dopamine neurons for disease.Roles of palmitoylation in axon growth, degeneration and regeneration.Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases.Axon degeneration: make the Schwann cell great again.The microtubule-severing protein fidgetin acts after dendrite injury to promote their degeneration.A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy.Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy.Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104.GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration.The axon degeneration gene SARM1 is evolutionarily distinct from other TIR domain-containing proteins.Avian axons undergo Wallerian degeneration after injury and stress.Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy.Expression and regulation of the ERK1/2 and p38 MAPK signaling pathways in periodontal tissue remodeling of orthodontic tooth movement.Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation.NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes.Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling.The Influence of Nicotinamide on Health and Disease in the Central Nervous System.The Axon-Myelin Unit in Development and Degenerative DiseasePathological classification of equine recurrent laryngeal neuropathyPhosphatidylserine Externalization Results from and Causes Neurite Degeneration in Drosophila
P2860
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P2860
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
@en
type
label
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
@en
prefLabel
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
@en
P2093
P2860
P1433
P1476
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
@en
P2093
Aaron DiAntonio
Daniel W Summers
Josiah Gerdts
P2860
P304
P356
10.1016/J.NEURON.2015.12.023
P407
P577
2016-02-01T00:00:00Z