about
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cellsE2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivoIntegrative analysis of histone ChIP-seq and transcription data using Bayesian mixture models.spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data.A novel partial modification at C2501 in Escherichia coli 23S ribosomal RNALoss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineageLipocalin 2 is protective against E. coli pneumonia.C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4.Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes.Phosphorylation of serine 248 of C/EBPα is dispensable for myelopoiesis but its disruption leads to a low penetrant myeloid disorder with long latency.The multifaceted functions of C/EBPα in normal and malignant haematopoiesis.Messenger RNA surveillance: neutralizing natural nonsense.UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome.Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3.Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq.shRNA screening identifies JMJD1C as being required for leukemia maintenance.Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis.Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AMLPSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2.UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts.Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patternsSystems biology of neutrophil differentiation and immune response.C/EBPalpha: a tumour suppressor in multiple tissues?Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteriesC/EBPalpha in leukemogenesis: identity and origin of the leukemia-initiating cell.Gene expression profiling in MDS and AML: potential and future avenues.The functional consequences of intron retention: alternative splicing coupled to NMD as a regulator of gene expression.Initiation of MLL-rearranged AML is dependent on C/EBPαNMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionalitymicroRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus.Technical advance: immunophenotypical characterization of human neutrophil differentiation.The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia.Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel.BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis.Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils.
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P50
description
hulumtues
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հետազոտող
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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Bo Torben Porse
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0000-0001-6043-0844