shRNA screening identifies JMJD1C as being required for leukemia maintenance.
about
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia.Epigenetic drugs against cancer: an evolving landscape.The molecular mechanics of mixed lineage leukemia.Histone demethylase RBP2 decreases miR-21 in blast crisis of chronic myeloid leukemia.Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia MaintenanceJMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors.Digging deep into "dirty" drugs - modulation of the methylation machinery.MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C.DNA damage accumulation and repair defects in acute myeloid leukemia: implications for pathogenesis, disease progression, and chemotherapy resistance.KDM3B shows tumor-suppressive activity and transcriptionally regulates HOXA1 through retinoic acid response elements in acute myeloid leukemia.The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia.A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality.Lysine-specific histone demethylases in normal and malignant hematopoiesis.Epigenetic therapies by targeting aberrant histone methylome in AML: molecular mechanisms, current preclinical and clinical development.Replication and hematological characterization of human platelet reactivity genetic associations in men from the Caerphilly Prospective Study (CaPS).Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.Feature genes predicting the FLT3/ITD mutation in acute myeloid leukemiaJMJD1C Ensures Mouse Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming through Controlling MicroRNA Expression.Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell deathComplementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia.The chromatin-remodeling factor CHD4 is required for maintenance of childhood acute myeloid leukemia.The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia.Epigenetic regulation of NFE2 overexpression in myeloproliferative neoplasms.Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2.
P2860
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P2860
shRNA screening identifies JMJD1C as being required for leukemia maintenance.
description
2014 nî lūn-bûn
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2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2014 թվականի փետրվարին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
shRNA screening identifies JMJD1C as being required for leukemia maintenance.
@ast
shRNA screening identifies JMJD1C as being required for leukemia maintenance.
@en
type
label
shRNA screening identifies JMJD1C as being required for leukemia maintenance.
@ast
shRNA screening identifies JMJD1C as being required for leukemia maintenance.
@en
prefLabel
shRNA screening identifies JMJD1C as being required for leukemia maintenance.
@ast
shRNA screening identifies JMJD1C as being required for leukemia maintenance.
@en
P2093
P50
P1433
P1476
shRNA screening identifies JMJD1C as being required for leukemia maintenance.
@en
P2093
John-Paul Bukowski
Julian Walfridsson
Patrycja Sroczynska
Satoru Miyagi
V Adam Cruickshank
P304
P356
10.1182/BLOOD-2013-08-522094
P407
P577
2014-02-05T00:00:00Z