Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy.
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Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease inductionp8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growthp8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein IThe pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypertAngiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cellsStress-inducible protein p8 is involved in several physiological and pathological processes.Brief report: stress-inducible nuclear protein 1 regulates matrix metalloproteinase 13 expression in human articular chondrocytes.Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function.From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypesGrowth factor midkine is involved in the pathogenesis of diabetic nephropathy.Microvascular basement membranes in diabetes mellitus.Physiology and pathology of endothelin-1 in renal mesangium.Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8.Expression of p8 in Human Oral Squamous Cell Carcinoma.Regulation of blood pressure and salt homeostasis by endothelin.Expression and roles of NUPR1 in cholangiocarcinoma cellsThe Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling PathwayThe transcription factor p8 regulates autophagy during diapause embryo formation in Artemia parthenogenetica.FOG2 protein down-regulation by transforming growth factor-β1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy.Physiology of endothelin and the kidney.Activation of PI3K in response to high glucose leads to regulation of SOCS-3 and STAT1/3 signals and induction of glomerular mesangial extracellular matrix formation.Leptin induces rat glomerular mesangial cell hypertrophy, but does not regulate hyperplasia or apoptosis.p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage.Trifluoperazine Inhibits Mesangial Cell Proliferation by Arresting Cell Cycle-Dependent MechanismsGene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling.Oxidative stress-responsive transcription factor ATF3 potentially mediates diabetic angiopathy.Growth arrest-specific gene 6 is involved in glomerular hypertrophy in the early stage of diabetic nephropathy.Renal damage in the SHR/N-cp type 2 diabetes model: comparison of an angiotensin-converting enzyme inhibitor and endothelin receptor blocker.Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathy.Renal medullary gene expression in aquaporin-1 null mice.Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo.Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products.YAP-TEAD signaling promotes basal cell carcinoma development via a c-JUN/AP1 axis
P2860
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P2860
Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Signaling pathways and late-on ...... al mesangial cell hypertrophy.
@en
type
label
Signaling pathways and late-on ...... al mesangial cell hypertrophy.
@en
prefLabel
Signaling pathways and late-on ...... al mesangial cell hypertrophy.
@en
P2093
P2860
P356
P1433
P1476
Signaling pathways and late-on ...... al mesangial cell hypertrophy.
@en
P2093
John M Kyriakis
Joseph V Bonventre
Sandro Goruppi
P2860
P304
P356
10.1093/EMBOJ/CDF535
P407
P577
2002-10-01T00:00:00Z