Mechanism of activation of protein kinase B by insulin and IGF-1
about
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activationActivation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cellsRequirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytesRegulation of endothelium-derived nitric oxide production by the protein kinase AktDAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositidesCharacterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinaseNIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificitiesPhosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase AThe kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation siteEvidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivoThe mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activitySKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation.A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambdaSystematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent mannermTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptideAkt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factorAkt is negatively regulated by the MULAN E3 ligaseShepherding AKT and androgen receptor by Ack1 tyrosine kinaseKank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signalingSemaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathwayHeat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator ProteinPar-4 inhibits Akt and suppresses Ras-induced lung tumorigenesisMitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREBEssential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signallingAn analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitroWNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrateActivation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alphaRole of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivoThe PI3K-PDK1 connection: more than just a road to PKBRegulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155Phosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinaseSynergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through AktSerum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathwayA phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.
P2860
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P2860
Mechanism of activation of protein kinase B by insulin and IGF-1
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Mechanism of activation of protein kinase B by insulin and IGF-1
@ast
Mechanism of activation of protein kinase B by insulin and IGF-1
@en
Mechanism of activation of protein kinase B by insulin and IGF-1
@en-gb
Mechanism of activation of protein kinase B by insulin and IGF-1
@nl
type
label
Mechanism of activation of protein kinase B by insulin and IGF-1
@ast
Mechanism of activation of protein kinase B by insulin and IGF-1
@en
Mechanism of activation of protein kinase B by insulin and IGF-1
@en-gb
Mechanism of activation of protein kinase B by insulin and IGF-1
@nl
prefLabel
Mechanism of activation of protein kinase B by insulin and IGF-1
@ast
Mechanism of activation of protein kinase B by insulin and IGF-1
@en
Mechanism of activation of protein kinase B by insulin and IGF-1
@en-gb
Mechanism of activation of protein kinase B by insulin and IGF-1
@nl
P2093
P2860
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P1476
Mechanism of activation of protein kinase B by insulin and IGF-1
@en
P2093
P2860
P304
P3181
P356
10.1002/J.1460-2075.1996.TB01045.X
P407
P577
1996-12-01T00:00:00Z