Wnt activation and alternative promoter repression of LEF1 in colon cancer. - Test2 - elhamkhani - TriplyDB

Wnt activation and alternative promoter repression of LEF1 in colon cancer.

Wnt activation and alternative promoter repression of LEF1 in colon cancer.

http://www.wikidata.org/entity/Q38406319

about

Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development Progenitor cells in proximal airway epithelial development and regeneration Regulatory gene network circuits underlying T cell development from multipotent progenitors Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials Gene expression network analyses in response to air pollution exposures in the trucking industry Higher Matrix Stiffness Upregulates Osteopontin Expression in Hepatocellular Carcinoma Cells Mediated by Integrin β1/GSK3β/β-Catenin Signaling Pathway TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response Sox17 modulates Wnt3A/beta-catenin-mediated transcriptional activation of the Lef-1 promoter.HIV's Nef interacts with β-catenin of the Wnt signaling pathway in HEK293 cells A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription Comparative profiling of primary colorectal carcinomas and liver metastases identifies LEF1 as a prognostic biomarker MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression.A role for YY1 in repression of dominant negative LEF-1 expression in colon cancer MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression.The balance between two isoforms of LEF-1 regulates colon carcinoma growth LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1 Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2.Lef1DeltaN binds beta-catenin and increases osteoblast activity and trabecular bone mass.T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis.Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancer Histone deacetylase 10 suppresses proliferation and invasion by inhibiting the phosphorylation of β-catenin and serves as an independent prognostic factor for human clear cell renal cell carcinoma.IFNγ Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer.Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis.Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.PITX2 and beta-catenin interactions regulate Lef-1 isoform expression.Gene expression profiling of the synergy of 5-aza-2'-deoxycytidine and paclitaxel against renal cell carcinoma.Raw mediates antagonism of AP-1 activity in Drosophila.Diversity of LEF/TCF action in development and disease.The glandular stem/progenitor cell niche in airway development and repair.A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis.Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients.Tissue-specific alternative splicing of TCF7L2.Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation.Sox2 modulates Lef-1 expression during airway submucosal gland development.Wnt signaling and colon carcinogenesis: beyond APC.TCF/LEFs and Wnt signaling in the nucleus.Expression of different functional isoforms in haematopoiesis.β-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice.

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P2860

Wnt activation and alternative promoter repression of LEF1 in colon cancer.

http://www.wikidata.org/entity/Q38406319

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

@zh-cn

name

Wnt activation and alternative promoter repression of LEF1 in colon cancer.

@en

type

label

Wnt activation and alternative promoter repression of LEF1 in colon cancer.

@en

prefLabel

Wnt activation and alternative promoter repression of LEF1 in colon cancer.

@en

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P1433

Molecular and Cellular Biology

P1476

Wnt activation and alternative promoter repression of LEF1 in colon cancer.

@en

P2093

Alla Bernstein

http://www.w3.org/2001/XMLSchema#string

Ju-Hui T Ting

http://www.w3.org/2001/XMLSchema#string

Marc van de Wetering

http://www.w3.org/2001/XMLSchema#string

Marian L Waterman

http://www.w3.org/2001/XMLSchema#string

Noriko N Yokoyama

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Tony W-H Li

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P2860

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein

Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing.

The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity

All Tcf HMG box transcription factors interact with Groucho-related co-repressors

Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

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5284-5299

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scholarly article

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10.1128/MCB.00105-06

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14

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26

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Marc van de Wetering

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2006-07-01T00:00:00Z

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16809766

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1592719

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