Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity.
about
Decreased mitochondrial DNA copy number in the hippocampus and peripheral blood during opiate addiction is mediated by autophagy and can be salvaged by melatoninMelatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways.Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012 - 2014).Cellular prion protein (PrP(C)) and its role in stress responses.Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux.Gene and protein patterns of potential prion-related markers in the central nervous system of clinical and preclinical infected sheepRecent advances in autophagy-based neuroprotection.Melatonin-mediated β-catenin activation protects neuron cells against prion protein-induced neurotoxicity.Gingerol-induced hypoxia-inducible factor 1 alpha inhibits human prion peptide-mediated neurotoxicity.The implication of neuronimmunoendocrine (NIE) modulatory network in the pathophysiologic process of Parkinson's disease.Role of simvastatin and RORα activity in the macrophage apoptotic pathway.Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells.Melatonin regulates the autophagic flux via activation of alpha-7 nicotinic acetylcholine receptors.Melatonin reverses H2 O2 -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB.C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis via regulating mitochondrial homeostasis.Lysosomal Quality Control in Prion Diseases.Melatonin modulates the autophagic response in acute liver failure induced by the rabbit hemorrhagic disease virus.Long-term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle-aged Ts65Dn mice, a model of Down syndrome.Delay in leaf senescence of Malus hupehensis by long-term melatonin application is associated with its regulation of metabolic status and protein degradation.Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway.Melatonin induces autophagy via an mTOR-dependent pathway and enhances clearance of mutant-TGFBIp.Autophagic flux induced by graphene oxide has a neuroprotective effect against human prion protein fragments.Long-term melatonin treatment delays ovarian aging.Melatonin enhances the occurrence of autophagy induced by oxidative stress in Arabidopsis seedlings.Involvement of autophagy in melatonin-induced cytotoxicity in glioma-initiating cells.Melatonin Ameliorates Arsenite-Induced Neurotoxicity: Involvement of Autophagy and Mitochondria.Melatonin suppresses nitric oxide production in glial cultures by pro-inflammatory cytokines through p38 MAPK inhibition.
P2860
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P2860
Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity.
@en
type
label
Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity.
@en
prefLabel
Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity.
@en
P2093
P2860
P921
P1476
Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity.
@en
P2093
Jae-Kyo Jeong
Jae-Won Seol
Myung-Hee Moon
Sang-Youel Park
You-Jin Lee
P2860
P304
P356
10.1111/J.1600-079X.2012.00980.X
P577
2012-02-16T00:00:00Z