Halogenase Engineering for the Generation of New Natural Product Analogues.
about
Accessing Nature's diversity through metabolic engineering and synthetic biologyStructure and biocatalytic scope of thermophilic flavin-dependent halogenase and flavin reductase enzymesHarnessing natural product assembly lines: structure, promiscuity, and engineering.Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.Discovery of a Promiscuous Non-Heme Iron Halogenase in Ambiguine Alkaloid Biogenesis: Implication for an Evolvable Enzyme Family for Late-Stage Halogenation of Aliphatic Carbons in Small Molecules.Enzymatic site-selectivity enabled by structure-guided directed evolution.Regioselective Dichlorination of a Non-Activated Aliphatic Carbon Atom and Phenolic Bismethylation by a Multifunctional Fungal Flavoenzyme.Formation and structure of the ferryl [Fe[double bond, length as m-dash]O] intermediate in the non-haem iron halogenase SyrB2: classical and QM/MM modelling agree.Structure-Guided Reprogramming of a Hydroxylase To Halogenate Its Small Molecule Substrate.Accelerating the semisynthesis of alkaloid-based drugs through metabolic engineering.Understanding and Improving the Activity of Flavin-Dependent Halogenases via Random and Targeted Mutagenesis.Expanding beyond canonical metabolism: Interfacing alternative elements, synthetic biology, and metabolic engineering.Two-Component FAD-Dependent Monooxygenases: Current Knowledge and Biotechnological Opportunities
P2860
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P2860
Halogenase Engineering for the Generation of New Natural Product Analogues.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Halogenase Engineering for the Generation of New Natural Product Analogues.
@en
type
label
Halogenase Engineering for the Generation of New Natural Product Analogues.
@en
prefLabel
Halogenase Engineering for the Generation of New Natural Product Analogues.
@en
P2860
P356
P1433
P1476
Halogenase Engineering for the Generation of New Natural Product Analogues.
@en
P2093
Sarah E O'Connor
Stephanie Brown
P2860
P304
P356
10.1002/CBIC.201500338
P577
2015-08-10T00:00:00Z