MacroEvoLution: A New Method for the Rapid Generation of Novel Scaffold-Diverse Macrocyclic Libraries

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MacroEvoLution: A New Method for the Rapid Generation of Novel Scaffold-Diverse Macrocyclic Libraries

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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MacroEvoLution: A New Method f ...... -Diverse Macrocyclic Libraries

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type

Item

label

MacroEvoLution: A New Method f ...... -Diverse Macrocyclic Libraries

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MacroEvoLution: A New Method f ...... -Diverse Macrocyclic Libraries

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P1476

MacroEvoLution: A New Method f ...... -Diverse Macrocyclic Libraries

@en

P2093

Lars Ole Haustedt

http://www.w3.org/2001/XMLSchema#string

Oliver Kunz

http://www.w3.org/2001/XMLSchema#string

Sven Jakupovic

http://www.w3.org/2001/XMLSchema#string

P2860

What can a chemist learn from nature's macrocycles?--a brief, conceptual view.

Production of cyclic peptides and proteins in vivo

New inhibitors of bacterial protein synthesis from a combinatorial library of macrocycles.

Probing the Physicochemical Boundaries of Cell Permeability and Oral Bioavailability in Lipophilic Macrocycles Inspired by Natural Products.

Molecular shape diversity of combinatorial libraries: a prerequisite for broad bioactivity.

Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli.

In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors

An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.

Fragment-based domain shuffling approach for the synthesis of pyran-based macrocycles.

A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling.

P304

11784-11791

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P31

scholarly article

P356

10.1002/CHEM.201703209

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Jörn Saupe

Christian Mang

P577

2017-08-07T00:00:00Z

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P698

28715083

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P921

macroevolution

P932

5601232

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