Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.
about
Hepatitis B: progress in understanding chronicity, the innate immune response, and cccDNA protectionComparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 ComplexGenome-wide identification of direct HBx genomic targetsInterplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts.The Role of cccDNA in HBV Maintenance.Proteomic profiling of HBV infected liver biopsies with different fibrotic stages.The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after InfectionThe ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection.DDB1 Stimulates Viral Transcription of Hepatitis B Virus via HBx-Independent Mechanisms.Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication.Hepatitis B Virus Protein X Induces Degradation of Talin-1.Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs.LUC7L3/CROP inhibits replication of hepatitis B virus via suppressing enhancer II/basal core promoter activity.Evolving New Strategies for the Medical Management of Chronic Hepatitis B Virus Infection.Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase.HBV DNA Integration: Molecular Mechanisms and Clinical ImplicationsHBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis.Hepatitis B Virus Capsid Assembly Modulators, but Not Nucleoside Analogs, Inhibit the Production of Extracellular Pregenomic RNA and Spliced RNA VariantsThe current status and future directions of hepatitis B antiviral drug discovery.Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer.Novel targets for hepatitis B virus therapy.Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6.A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation-and Beyond?Viral hepatitis and liver cancer.Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication.Epigenetic Regulation of Hepatitis B Virus Covalently Closed Circular DNA: Implications for Epigenetic Therapy against Chronic Hepatitis B.Recombinant cccDNA of hepatitis B virus induces long-term viral persistence with chronic hepatitis in a mouse model.New Direct-Acting Antiviral Agents and Immunomodulators for Hepatitis B Virus Infection.[Personalized treatment of viral hepatitis of the present and the future : Hepatitis B, C, delta, and E].HBx-elevated MSL2 Modulates HBV cccDNA through Inducing Degradation of APOBEC3B to Enhance Hepatocarcinogenesis.Inducible Rubicon facilitates viral replication by antagonizing interferon production.Cullin-RING E3 Ubiquitin Ligases: Bridges to Destruction.4th European Seminars in Virology on Oncogenic and Oncolytic Viruses, in Bertinoro (Bologna), Italy.[A new restriction factor against HBV infection: the SMC5/6 complex].The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state.Virology: The X-Files of hepatitis B.Hepatitis B cure: From discovery to regulatory approval.The Structural Biology of Hepatitis B Virus: Form and Function.Hepatitis B virus X protein crosses out Smc5/6 complex to maintain covalently closed circular DNA transcription.Hepatitis B Virus and DNA Damage Response: Interactions and Consequences for the Infection.
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P2860
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.
@en
type
label
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.
@en
prefLabel
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.
@en
P2093
P2860
P356
P1433
P1476
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor
@en
P2093
Adrien Decorsière
Christine M Livingston
Congrong Niu
Fabien Abdul
Henrik Mueller
Michel Strubin
Olivier Hantz
Pieter C van Breugel
Rudolf K Beran
Simon P Fletcher
P2860
P2888
P304
P356
10.1038/NATURE17170
P407
P577
2016-03-01T00:00:00Z
P6179
1046028879