Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks
about
Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID FamiliesMAGE-RING protein complexes comprise a family of E3 ubiquitin ligasesIdentification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complexAPRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancerThe SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteinsThe cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cellsA polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cellIdentification of a novel, widespread, and functionally important PCNA-binding motifMechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathiesThe ancient and evolving roles of cohesin in gene expression and DNA repairSumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution.Replication stress in Mammalian cells and its consequences for mitosisScc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting WaplOligo/polynucleotide-based gene modification: strategies and therapeutic potentialHistone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatidDisruption of CHTF18 causes defective meiotic recombination in male miceComparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cellsRole for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis.Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatinZNF198 stabilizes the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingersStructural maintenance of chromosomes (SMC) proteins promote homolog-independent recombination repair in meiosis crucial for germ cell genomic stability.Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice.Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation.Rtt107 phosphorylation promotes localisation to DNA double-stranded breaks (DSBs) and recombinational repair between sister chromatids.Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease.The Smc5-Smc6 complex is required to remove chromosome junctions in meiosis.Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1.Mechanisms and principles of homology search during recombination.Cohesin protects genes against γH2AX Induced by DNA double-strand breaks.Homologous recombination-dependent rescue of deficiency in the structural maintenance of chromosomes (Smc) 5/6 complex.The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection.Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair.SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaksNuclear organization in genome stability: SUMO connections.The AtRAD21.1 and AtRAD21.3 Arabidopsis cohesins play a synergistic role in somatic DNA double strand break damage repair.Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewalATPase-dependent control of the Mms21 SUMO ligase during DNA repair.Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexesThe Use of Laser Microirradiation to Investigate the Roles of Cohesins in DNA Repair.NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity
P2860
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P2860
Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@ast
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@en
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@en-gb
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
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type
label
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@ast
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@en
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@en-gb
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@nl
prefLabel
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@ast
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@en
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@en-gb
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
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P2093
P2860
P921
P356
P1433
P1476
Human SMC5/6 complex promotes ...... omplex to double-strand breaks
@en
P2093
Hongtao Yu
Matthew H Porteus
Patrick Ryan Potts
P2860
P304
P356
10.1038/SJ.EMBOJ.7601218
P407
P577
2006-07-26T00:00:00Z