Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases

Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases

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http://www.wikidata.org/entity/Q38943944
Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers.APOBEC3A efficiently deaminates methylated, but not TET-oxidized, cytosine bases in DNA.A novel class of chemicals that react with abasic sites in DNA and specifically kill B cell cancers.APOBEC3A is Upregulated by Human Cytomegalovirus in the Maternal-Fetal Interface, Acting as an Innate Anti-HCMV Effector.HPV11 E6 mutation by overexpression of APOBEC3A and effects of interferon-ω on APOBEC3s and HPV11 E6 expression in HPV11.HaCaT cells.Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.Viral subversion of APOBEC3s: Lessons for anti-tumor immunity and tumor immunotherapy.Mechanisms for targeted, purposeful mutation revealed in an APOBEC-DNA complex.Harnessing natural DNA modifying activities for editing of the genome and epigenome.Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment.Characterization of BK Polyomaviruses from Kidney Transplant Recipients Suggests a Role for APOBEC3 in Driving In-Host Virus Evolution.Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid LigandsGenetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 proteaseOnset of deaminase APOBEC3B induction in response to DNA double-strand breaksStrategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity
P2860

Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases

Item
http://www.wikidata.org/entity/Q38943944
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases
@en
type
label
Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases
@en
prefLabel
Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932
P356
P1433
P1476
Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases
@en
P2093
P2860
P304
P31
P356
10.1021/ACS.CHEMREV.6B00296
P433
P478
P577
P698
P932