Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.
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Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment.Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens.Epigenome profiling and editing of neocortical progenitor cells during development.Epigenetic Regulation of the Epithelial to Mesenchymal Transition in Lung Cancer.Epigenetic plasticity and the hallmarks of cancer.Epstein-Barr virus: a master epigenetic manipulator.MUC1-C activates EZH2 expression and function in human cancer cells.Polycomb Repressor Complex 2 in Genomic Instability and CancerSWI/SNF complex in cancerIntegrative analysis of genomic and epigenomic regulation of the transcriptome in liver cancer.Notch Signaling Controls Transdifferentiation of Pulmonary Neuroendocrine Cells in Response to Lung Injury.Alternative Splicing of EZH2 pre-mRNA by SF3B3 Contributes to the Tumorigenic Potential of Renal Cancer.A missense variant in EZH2 is associated with colorectal cancer risk in a Chinese population.PRC2-mediated repression of SMARCA2 predicts EZH2 inhibitor activity in SWI/SNF mutant tumors.Polycomb-like proteins link the PRC2 complex to CpG islands.Structure, mechanism, and regulation of polycomb repressive complex 2.Multiple roles of Ring 1 and YY1 binding protein in physiology and disease.MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells.Tetracycline-controllable artificial microRNA-HOTAIR + EZH2 suppressed the progression of bladder cancer cells.Oncohistones: drivers of pediatric cancers.PRC2 Is Dispensable in Vivo for β-Catenin-Mediated Repression of Chondrogenesis in the Mouse Embryonic Cranial Mesenchyme.Mbf1 ensures Polycomb silencing by protecting E(z) mRNA from degradation by Pacman.Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation.Chromatin biology: Breaking into the PRC2 cage.Epigenetics and MicroRNAs in Cancer.Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin.Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity.Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.Epigenetic and Transcriptional Pre-patterning—An Emerging Theme in Cortical Neurogenesis.Cancer epigenetics: Moving forward.Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program.Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunitsARID1A-deficiency in urothelial bladder cancer: No predictive biomarker for EZH2-inhibitor treatment response?Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanismsMultiple polycomb epigenetic regulatory proteins are active in normal and regenerating adult olfactory epitheliumAccurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA ReplicationUnbiased shRNA screening, using a combination of FACS and high-throughput sequencing, enables identification of novel modifiers of Polycomb silencingThe long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p
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P2860
Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.
@en
type
label
Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.
@en
prefLabel
Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.
@en
P2860
P50
P356
P1476
Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.
@en
P2860
P2888
P304
P356
10.1038/NRC.2016.83
P407
P577
2016-09-23T00:00:00Z
P6179
1027309366