A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.
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The search for cis-regulatory driver mutations in cancer genomesReserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implicationsLimited evidence that cancer susceptibility regions are preferential targets for somatic mutationGenome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma.Five endometrial cancer risk loci identified through genome-wide association analysis.GREM1 and POLE variants in hereditary colorectal cancer syndromes.Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer.The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progressionAberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche.Germline deletions in the tumour suppressor gene FOCAD are associated with polyposis and colorectal cancer development.Association between polymorphisms at the GREM1 locus and the risk of nonsyndromic cleft lip with or without cleft palate in the Polish population.A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site.Gremlin and renal diseases: ready to jump the fence to clinical utility?
P2860
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P2860
A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
A polymorphic enhancer near GR ...... ntial CDX2 and TCF7L2 binding.
@en
type
label
A polymorphic enhancer near GR ...... ntial CDX2 and TCF7L2 binding.
@en
prefLabel
A polymorphic enhancer near GR ...... ntial CDX2 and TCF7L2 binding.
@en
P2093
P2860
P50
P1433
P1476
A polymorphic enhancer near GR ...... ntial CDX2 and TCF7L2 binding.
@en
P2093
Emma Jaeger
Gareth Bond
Hayley Davis
Hendrik G Stunnenberg
Luan N Nguyen
Luke Freeman-Mills
Martin Becker
Nina C Hubner
Simon Leedham
P2860
P304
P356
10.1016/J.CELREP.2014.07.020
P50
P577
2014-08-14T00:00:00Z