Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
about
Inhibition of Protein-Protein Interactions: New Options for Developing Drugs against Neglected Tropical Diseases.Repurposing of Human Kinase Inhibitors in Neglected Protozoan Diseases.Screening a Natural Product-Based Library against Kinetoplastid Parasites.Development of Predictive QSAR Models of 4-Thiazolidinones Antitrypanosomal Activity using Modern Machine Learning Algorithms.The Trypanocidal Effect of Novel Quinolines: In vitro And In vivo Studies.Barcoding in trypanosomes.Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity.An RNA polymerase II-associated TFIIF-like complex is indispensable for SL RNA gene transcription in Trypanosoma brucei.Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A.Genetically Validated Drug Targets in Leishmania; Current Knowledge and Future Prospects.Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases.Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles.Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis.African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System.Characterisation of a Putative Glutamate 5- Kinase from Leishmania donovani.Inducible high-efficiency CRISPR-Cas9-targeted gene editing and precision base editing in African trypanosomes.Innovation in neglected tropical disease drug discovery and development.Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasisDevelopment of an automated image analysis protocol for quantification of intracellular forms of Leishmania sppClinical and veterinary trypanocidal benzoxaboroles target CPSF3Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition MetalsAnti-trypanosomatid drug discovery: an ongoing challenge and a continuing needChallenges and recent progress in drug discovery for tropical diseases
P2860
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P2860
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
@en
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
@nl
type
label
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
@en
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
@nl
prefLabel
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
@en
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
@nl
P2093
P2860
P50
P356
P1476
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
@en
P2093
Kevin D Read
Leah S Torrie
Mark C Field
Michael A J Ferguson
Paul G Wyatt
P2860
P2888
P304
P356
10.1038/NRMICRO.2016.193
P407
P577
2017-02-27T00:00:00Z
P6179
1084129745