Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.
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Ribose 5-phosphate isomerase B knockdown compromises Trypanosoma brucei bloodstream form infectivityPyrimidine Salvage Enzymes Are Essential for De Novo Biosynthesis of Deoxypyrimidine Nucleotides in Trypanosoma bruceiThe Open Form Inducer Approach for Structure-Based Drug Design.The role of the de novo pyrimidine biosynthetic pathway in Cryptococcus neoformans high temperature growth and virulence.Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei.The Role of Folate Transport in Antifolate Drug Action in Trypanosoma brucei.Pyrimidine metabolism in schistosomes: A comparison with other parasites and the search for potential chemotherapeutic targets.Fresh insights into the pyrimidine metabolism in the trypanosomatids.
P2860
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P2860
Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.
description
2013 nî lūn-bûn
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name
Trypanosoma brucei (UMP syntha ...... taining pyrimidine auxotrophy.
@en
Trypanosoma brucei (UMP syntha ...... taining pyrimidine auxotrophy.
@nl
type
label
Trypanosoma brucei (UMP syntha ...... taining pyrimidine auxotrophy.
@en
Trypanosoma brucei (UMP syntha ...... taining pyrimidine auxotrophy.
@nl
prefLabel
Trypanosoma brucei (UMP syntha ...... taining pyrimidine auxotrophy.
@en
Trypanosoma brucei (UMP syntha ...... taining pyrimidine auxotrophy.
@nl
P2860
P50
P356
P1476
Trypanosoma brucei (UMP syntha ...... taining pyrimidine auxotrophy.
@en
P2093
Natasha Sienkiewicz
Stephen Patterson
P2860
P304
P356
10.1111/MMI.12376
P407
P577
2013-09-09T00:00:00Z