Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
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Twenty Years on: What Do We Really Know about Ewing Sarcoma and What Is the Path Forward?RhoGTPases as key players in mammalian cell adaptation to microgravityThe E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis.Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration.NKX6.3 Regulates Reactive Oxygen Species Production by Suppressing NF-kB and DNMT1 Activities in Gastric Epithelial Cells.Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addictionPLGA-Loaded Gold-Nanoparticles Precipitated with Quercetin Downregulate HDAC-Akt Activities Controlling Proliferation and Activate p53-ROS Crosstalk to Induce Apoptosis in Hepatocarcinoma Cells.Platelet Extracellular Regulated Protein Kinase 5 Is a Redox Switch and Triggers Maladaptive Platelet Responses and Myocardial Infarct ExpansionDosage-dependent role of Rac1 in podocyte injury.The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate.HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets.HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.NADPH Oxidases in Chronic Liver DiseasesE3 ubiquitin ligases in regulating stress fiber, lamellipodium, and focal adhesion dynamics.Rho GTPases, their post-translational modifications, disease-associated mutations and pharmacological inhibitors.Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress.New Aspects on Bacterial Effectors Targeting Rho GTPases.A rapid and effective method for screening, sequencing and reporter verification of engineered frameshift mutations in zebrafish.Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression.Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.NOX1-induced accumulation of reactive oxygen species in abdominal fat-derived mesenchymal stromal cells impinges on long-term proliferation.HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production.hace1 Influences zebrafish cardiac development via ROS-dependent mechanisms.Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.Overexpression of HACE1 in gastric cancer inhibits tumor aggressiveness by impeding cell proliferation and migration.Rho GTPases in Intellectual Disability: From Genetics to Therapeutic Opportunities.p104 binds to Rac1 and reduces its activity during myotube differentiation of C2C12 cell
P2860
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P2860
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
@en
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
@nl
type
label
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
@en
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
@nl
prefLabel
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
@en
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
@nl
P2093
P2860
P50
P356
P1476
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
@en
P2093
Ameer Jarrar
Babak Razaghi
Barak Rotblat
Jason N Berman
Josef M Penninger
Lindsay McDonald
Poul H Sorensen
P2860
P2888
P356
10.1038/NCOMMS3180
P407
P50
P577
2013-01-01T00:00:00Z
P5875
P6179
1042671983