IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
about
Survivin - The inconvenient IAPSmall-molecule SMAC mimetics as new cancer therapeuticsThe Rac1 hypervariable region in targeting and signaling: a tail of many storiesThe E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis.Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasionRegulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligaseXIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cellPDR-1/hParkin negatively regulates the phagocytosis of apoptotic cell corpses in Caenorhabditis elegans.Nuclear Rac1 regulates the bFGF-induced neurite outgrowth in PC12 cells.AMPylation of Rho GTPases subverts multiple host signaling processes.SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradationInhibitor of apoptosis proteins as intracellular signaling intermediates.RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migrationA potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapyGeneral aspects and recent advances on bacterial protein toxins.A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation.Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells.Discoidin domain receptor 1 protein is a novel modulator of megakaryocyte-collagen interactionsIAP proteins as targets for drug development in oncologyThe Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular StressUbiquitin links to cytoskeletal dynamics, cell adhesion and migration.Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications.Ubiquitylation of active Rac1 by the E3 ubiquitin-ligase HACE1.Cell cycle regulation of Rho signaling pathways.Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists.The cytotoxic necrotizing factor 1 from E. coli: a janus toxin playing with cancer regulators.IAPs on the move: role of inhibitors of apoptosis proteins in cell migration.Small Rho GTPases in the control of cell shape and mobility.X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.E3 ubiquitin ligases in regulating stress fiber, lamellipodium, and focal adhesion dynamics.Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): A second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells.Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms.Rho GTPases, their post-translational modifications, disease-associated mutations and pharmacological inhibitors.New Aspects on Bacterial Effectors Targeting Rho GTPases.Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells.Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts.PKC activation sensitizes basal-like breast cancer cell lines to Smac mimetics.Ubiquitin-mediated regulation of RhoGTPase signalling: IAPs and HACE1 enter the fray.
P2860
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P2860
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@ast
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@en
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@en-gb
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@nl
type
label
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@ast
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@en
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@en-gb
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@nl
prefLabel
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@ast
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@en
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@en-gb
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
@en
P2093
Alejandro Carpy
Carrie L Anderson
Christiaan Karreman
Gregory S Harms
Gudula Schmidt
Jennifer C Hocking
Juliane Mooz
Kazuhiko Namikawa
Krishnaraj Rajalingam
Mika Ruonala
P2860
P3181
P356
10.1038/EMBOJ.2011.423
P407
P577
2012-01-04T00:00:00Z