New synthetic inhibitors of fatty acid synthase with anticancer activity.
about
Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugsA human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate siteCrystal structure of the human fatty acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibitionNovel epigallocatechin-3-gallate (EGCG) derivative as a new therapeutic strategy for reducing neuropathic pain after chronic constriction nerve injury in miceModulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasis.Alpha-2-glycoprotein 1(AZGP1) regulates biological behaviors of LoVo cells by down-regulating mTOR signaling pathway and endogenous fatty acid synthesis.Metformin-induced killing of triple-negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193bA strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.Role of cystathionine beta synthase in lipid metabolism in ovarian cancerProteomics of genetically engineered mouse mammary tumors identifies fatty acid metabolism members as potential predictive markers for cisplatin resistance.Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells.Adipocyte-derived players in hematologic tumors: useful novel targets?Fatty Acids and Breast Cancer: Make Them on Site or Have Them Delivered.Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.Metabolic Regulation of Apoptosis in Cancer.Recent advances in targeting the fatty acid biosynthetic pathway using fatty acid synthase inhibitors.HOXB1 restored expression promotes apoptosis and differentiation in the HL60 leukemic cell lineIdentification of a new scaffold for hsp90 C-terminal inhibition[6]-Gingerol inhibits de novo fatty acid synthesis and carnitine palmitoyltransferase-1 activity which triggers apoptosis in HepG2.Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling.Fatty acid synthase (FASN) as a therapeutic target in breast cancer.Combination Treatment with Orlistat-Containing Nanoparticles and Taxanes Is Synergistic and Enhances Microtubule Stability in Taxane-Resistant Prostate Cancer Cells.
P2860
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P2860
New synthetic inhibitors of fatty acid synthase with anticancer activity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
New synthetic inhibitors of fatty acid synthase with anticancer activity.
@en
New synthetic inhibitors of fatty acid synthase with anticancer activity.
@nl
type
label
New synthetic inhibitors of fatty acid synthase with anticancer activity.
@en
New synthetic inhibitors of fatty acid synthase with anticancer activity.
@nl
prefLabel
New synthetic inhibitors of fatty acid synthase with anticancer activity.
@en
New synthetic inhibitors of fatty acid synthase with anticancer activity.
@nl
P2093
P50
P356
P1476
New synthetic inhibitors of fatty acid synthase with anticancer activity.
@en
P2093
Adriana Blancafort
Bellinda Benhamú
Carlos Turrado
Diego Haro
Gloria Oliveras
Pedro F Marrero
Teresa Puig
P304
P356
10.1021/JM2016045
P407
P50
P577
2012-05-16T00:00:00Z