Role of the PAS domain in regulation of dimerization and DNA binding specificity of the dioxin receptor
about
The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptorThe hsp90 chaperone complex regulates intracellular localization of the dioxin receptorStructural basis for PAS domain heterodimerization in the basic helix-loop-helix-PAS transcription factor hypoxia-inducible factorStructure and Dimerization Properties of the Aryl Hydrocarbon Receptor PAS-A DomainAdaptor-Dependent Degradation of a Cell-Cycle Regulator Uses a Unique Substrate ArchitectureThe immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptorEvidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptorAn aryl hydrocarbon receptor conformation acts as the functional core of nuclear dioxin signaling.PAS domains: internal sensors of oxygen, redox potential, and lightOn the detection of functionally coherent groups of protein domains with an extension to protein annotation.The aryl hydrocarbon receptor nuclear transporter is modulated by the SUMO-1 conjugation system.Convergent evolution of gene networks by single-gene duplications in higher eukaryotes.PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady-state level of WC-1 and the function of both proteins in circadian clock and light responses of Neurospora.Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.Structure and signaling mechanism of Per-ARNT-Sim domains.The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcriptionRegulation of coronafacoyl phytotoxin production by the PAS-LuxR family regulator CfaR in the common scab pathogen Streptomyces scabies.Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response PathwayAnalysis of Ah receptor-ARNT and Ah receptor-ARNT2 complexes in vitro and in cell culture.ARNT2 Regulates Tumoral Growth in Oral Squamous Cell Carcinoma.The GCN4 bZIP can bind to noncognate gene regulatory sequences.NPAS3 is a trachealess homolog critical for lung development and homeostasisToxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway.Role of accessory factors and steroid receptor coactivator 1 in the regulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization.Regulation of the Drosophila hypoxia-inducible factor alpha Sima by CRM1-dependent nuclear export.Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt.Unique and overlapping transcriptional roles of arylhydrocarbon receptor nuclear translocator (Arnt) and Arnt2 in xenobiotic and hypoxic responses.Differential usage of nuclear export sequences regulates intracellular localization of the dioxin (aryl hydrocarbon) receptor.Characterization of the aryl hydrocarbon receptor repressor gene and association of its Pro185Ala polymorphism with micropenis.Definition of a dioxin receptor mutant that is a constitutive activator of transcription: delineation of overlapping repression and ligand binding functions within the PAS domain.Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2.Contribution of the Per/Arnt/Sim (PAS) domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators.Panax ginseng improves survival and sperm quality in guinea pigs exposed to 2,3,7,8-tetrachlorodibenzo- p-dioxin.The DNA target determines the dimerization partner selected by bHLHZ-like hybrid proteins AhRJun and ArntFos.Novel DNA binding by a basic helix-loop-helix protein. The role of the dioxin receptor PAS domain.Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.HIF-1α promotes autophagic proteolysis of Dicer and enhances tumor metastasis.Ligand-induced perturbation of the HIF-2α:ARNT dimer dynamics.
P2860
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P2860
Role of the PAS domain in regulation of dimerization and DNA binding specificity of the dioxin receptor
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Role of the PAS domain in regu ...... ificity of the dioxin receptor
@en
Role of the PAS domain in regu ...... ficity of the dioxin receptor.
@nl
type
label
Role of the PAS domain in regu ...... ificity of the dioxin receptor
@en
Role of the PAS domain in regu ...... ficity of the dioxin receptor.
@nl
prefLabel
Role of the PAS domain in regu ...... ificity of the dioxin receptor
@en
Role of the PAS domain in regu ...... ficity of the dioxin receptor.
@nl
P2093
P2860
P356
P1476
Role of the PAS domain in regu ...... ificity of the dioxin receptor
@en
P2093
Antonsson C
Poellinger L
Pongratz I
Whitelaw ML
P2860
P304
P356
10.1128/MCB.18.7.4079
P407
P577
1998-07-01T00:00:00Z