Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes.
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Gene copy-number polymorphism caused by retrotransposition in humansPseudogenes: pseudo-functional or key regulators in health and disease?HMGA1-pseudogenes and cancerProfiling RNA editing in human tissues: towards the inosinome AtlasNot so pseudo anymore: pseudogenes as therapeutic targetsNot so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenesHMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathwayThe High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development.Protein-Coding Genes' Retrocopies and Their Functions.Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic functionGene expression profile analysis identifies metastasis and chemoresistance-associated genes in epithelial ovarian carcinoma cells.LncRNAs expression in preeclampsia placenta reveals the potential role of LncRNAs contributing to preeclampsia pathogenesis.Transcriptional regulation of the HMGA1 gene by octamer-binding proteins Oct-1 and Oct-2.A novel mechanism of post-translational modulation of HMGA functions by the histone chaperone nucleophosmin.Pseudogenes transcribed in breast invasive carcinoma show subtype-specific expression and ceRNA potentialThe Association between HMGA1 rs146052672 Variant and Type 2 Diabetes: A Transethnic Meta-Analysis.A microdeletion at Xq22.2 implicates a glycine receptor GLRA4 involved in intellectual disability, behavioral problems and craniofacial anomalies.Differentially-Expressed Pseudogenes in HIV-1 InfectionA Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic PainHigh expression of dual-specificity phosphatase 5 pseudogene 1 (DUSP5P1) is associated with poor prognosis in acute myeloid leukemia.Differentially expressed, variant U1 snRNAs regulate gene expression in human cellsRegulatory mechanisms of long noncoding RNAs in vertebrate central nervous system development and functionA polymorphism of HMGA1 is associated with increased risk of metabolic syndrome and related componentsLong non-coding RNAs (lncRNAs) and viral infections.Pseudogenes as regulators of biological function.A polymorphism of HMGA1 protects against proliferative diabetic retinopathy by impairing HMGA1-induced VEGFA expression.Molecular Evolution of the Glycosyltransferase 6 Gene Family in Primates.Pseudogenes are not pseudo any more.Down-regulation of pseudogene Vimentin 2p is associated with poor outcome in de novo acute myeloid leukemia.Low-frequency variants in HMGA1 are not associated with type 2 diabetes riskCooperation between HMGA1, PDX-1, and MafA is Essential for Glucose-Induced Insulin Transcription in Pancreatic Beta CellsExpression of matrix metalloproteinase-11 is increased under conditions of insulin resistance.HMGA1P7-pseudogene regulates H19 and Igf2 expression by a competitive endogenous RNA mechanism.HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance.dreamBase: DNA modification, RNA regulation and protein binding of expressed pseudogenes in human health and disease.The HMGA1 Pseudogene 7 Induces miR-483 and miR-675 Upregulation by Activating Egr1 through a ceRNA Mechanism.HMGA1 is a novel transcriptional regulator of the FoxO1 gene.Type 2 Diabetes Mellitus and Cardiovascular Disease: Genetic and Epigenetic Links.PTEN/PTENP1: 'Regulating the regulator of RTK-dependent PI3K/Akt signalling', new targets for cancer therapy.The pseudogene-derived long non-coding RNA SFTA1P suppresses cell proliferation, migration, and invasion in gastric cancer.
P2860
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P2860
Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Pseudogene-mediated posttransc ...... esistance and type 2 diabetes.
@en
Pseudogene-mediated posttransc ...... esistance and type 2 diabetes.
@nl
type
label
Pseudogene-mediated posttransc ...... esistance and type 2 diabetes.
@en
Pseudogene-mediated posttransc ...... esistance and type 2 diabetes.
@nl
prefLabel
Pseudogene-mediated posttransc ...... esistance and type 2 diabetes.
@en
Pseudogene-mediated posttransc ...... esistance and type 2 diabetes.
@nl
P2093
P50
P356
P1476
Pseudogene-mediated posttransc ...... resistance and type 2 diabetes
@en
P2093
Biagio Arcidiacono
Ilaria Le Pera
Mirella Filocamo
Stefania Iiritano
Stephen A Liebhaber
P2860
P2888
P356
10.1038/NCOMMS1040
P407
P577
2010-07-27T00:00:00Z