p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
about
Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypesMdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cellsThe combination of BH3-mimetic ABT-737 with the alkylating agent temozolomide induces strong synergistic killing of melanoma cells independent of p53Noncanonical microRNAs and endogenous siRNAs in normal and psoriatic human skinA Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools.P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferationHigh-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assaysA polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection.E2F1-dependent oncogenic addiction of melanoma cells to MDM2.Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivoA prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell linesReactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor DisseminationMicroRNAs in normal and psoriatic skinWT1 shRNA delivery using transferrin-conjugated PEG liposomes in an in vivo model of melanoma.Advances in melanoma senescence and potential clinical application.Modelling melanoma in mice.Restoring the tumour suppressive function of p53 as a parallel strategy in melanoma therapy.Blinded by the light: why the treatment of metastatic melanoma has created a new paradigm for the management of cancer.Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p73 by oncolytic adenovirus.Dominant effects of Δ40p53 on p53 function and melanoma cell fateClinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients.Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.Nevus senescence.p53 targets TSPAN8 to prevent invasion in melanoma cells.Targeting p53 in melanoma.Pathways from senescence to melanoma: focus on MITF sumoylation.Neonatal UVB exposure accelerates melanoma growth and enhances distant metastases in Hgf-Cdk4(R24C) C57BL/6 mice.
P2860
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P2860
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
@en
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.
@nl
type
label
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
@en
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.
@nl
prefLabel
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
@en
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.
@nl
P2093
P2860
P50
P1476
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
@en
P2093
Dennis R Roop
Enrique C Torchia
Guillermina Lozano
Kazutoshi Murao
Marianne B Powell
Regan A Stiegmann
Steven E Robinson
Tamara Terzian
Victoria Gonzalez
P2860
P304
P356
10.1111/J.1755-148X.2010.00773.X
P577
2010-12-01T00:00:00Z