Covering a broad dynamic range: information processing at the erythropoietin receptor.
about
Cumulative signal transmission in nonlinear reaction-diffusion networksA computational model of liver iron metabolismDynamic ligand modulation of EPO receptor pools, and dysregulation by polycythemia-associated EPOR allelesL1 regularization facilitates detection of cell type-specific parameters in dynamical systems.Physiologically realistic and validated mathematical liver model reveals [corrected] hepatobiliary transfer rates for Gd-EOB-DTPA using human DCE-MRI data.Tracing the molecular basis of transcriptional dynamics in noisy data by using an experiment-based mathematical model.A method for zooming of nonlinear models of biochemical systems.LASSIM-A network inference toolbox for genome-wide mechanistic modeling.Prognostic significance of erythropoietin in pancreatic adenocarcinomaIn silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems.Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range.Experimental design for parameter estimation of gene regulatory networksBayesian model selection validates a biokinetic model for zirconium processing in humans.A protein turnover signaling motif controls the stimulus-sensitivity of stress response pathwaysLessons learned from quantitative dynamical modeling in systems biology.Receptor-based dosing optimization of erythropoietin in juvenile sheep after phlebotomy.iVUN: interactive Visualization of Uncertain biochemical reaction Networks.Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.Structural and functional protein network analyses predict novel signaling functions for rhodopsin.Emerging EPO and EPO receptor regulators and signal transducers.Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells.Driving the Model to Its Limit: Profile Likelihood Based Model ReductionWidespread expression of erythropoietin receptor in brain and its induction by injury.Darbepoietin-alfa has comparable erythropoietic stimulatory effects to recombinant erythropoietin whilst preserving the bone marrow microenvironmentPharmacodynamic analysis of stress erythropoiesis: change in erythropoietin receptor pool size following double phlebotomies in sheepImpact of host genetic polymorphisms on vaccine induced antibody responseProtein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation.T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.Predictive mathematical models of cancer signalling pathways.Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses.Profile likelihood in systems biology.Multifarious determinants of cytokine receptor signaling specificity.Cracking the NF-κB code.Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis.A Bayesian approach to estimating hidden variables as well as missing and wrong molecular interactions in ordinary differential equation-based mathematical models.A dimeric peptide with erythropoiesis-stimulating activity uniquely affects erythropoietin receptor ligation and cell surface expression.Comparison of approaches for parameter identifiability analysis of biological systems.Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway.Sensitivity control through attenuation of signal transfer efficiency by negative regulation of cellular signalling.Quantification of degeneracy in biological systems for characterization of functional interactions between modules.
P2860
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P2860
Covering a broad dynamic range: information processing at the erythropoietin receptor.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Covering a broad dynamic range: information processing at the erythropoietin receptor.
@en
Covering a broad dynamic range: information processing at the erythropoietin receptor.
@nl
type
label
Covering a broad dynamic range: information processing at the erythropoietin receptor.
@en
Covering a broad dynamic range: information processing at the erythropoietin receptor.
@nl
prefLabel
Covering a broad dynamic range: information processing at the erythropoietin receptor.
@en
Covering a broad dynamic range: information processing at the erythropoietin receptor.
@nl
P2093
P2860
P356
P1433
P1476
Covering a broad dynamic range: information processing at the erythropoietin receptor.
@en
P2093
Andreas Raue
Jens Timmer
Julie Bachmann
Thomas Maiwald
Ute Baumann
Verena Becker
P2860
P304
P356
10.1126/SCIENCE.1184913
P407
P577
2010-05-20T00:00:00Z