Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy.
about
The emerging role of viral vectors as vehicles for DMD gene editingAdvancements in stem cells treatment of skeletal muscle wastingA pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challengesStem cells for skeletal muscle regeneration: therapeutic potential and roadblocksPerspectives of stem cell therapy in Duchenne muscular dystrophyInflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMDTherapy of Genetic Disorders-Novel Therapies for Duchenne Muscular Dystrophy.Influence of immune responses in gene/stem cell therapies for muscular dystrophies.Gene and cell-mediated therapies for muscular dystrophy.Stem cell transplantation for muscular dystrophy: the challenge of immune response.The DMD locus harbours multiple long non-coding RNAs which orchestrate and control transcription of muscle dystrophin mRNA isoforms.Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy.Coaxing stem cells for skeletal muscle repairComplete restoration of multiple dystrophin isoforms in genetically corrected Duchenne muscular dystrophy patient-derived cardiomyocytes.PW1/Peg3 expression regulates key properties that determine mesoangioblast stem cell competence.A single epidermal stem cell strategy for safe ex vivo gene therapy.Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette.Mesoangioblast delivery of miniagrin ameliorates murine model of merosin-deficient congenital muscular dystrophy type 1A.Stable maintenance of de novo assembled human artificial chromosomes in embryonic stem cells and their differentiated progeny in mice.Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy.Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.piggyBac transposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts.Chromosome transplantation as a novel approach for correcting complex genomic disordersEngraftment of ES-Derived Myogenic Progenitors in a Severe Mouse Model of Muscular Dystrophy.The emerging biology of muscle stem cells: implications for cell-based therapies.Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function.Impaired regeneration: A role for the muscle microenvironment in cancer cachexia.Protecting a transgene expression from the HAC-based vector by different chromatin insulators.Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.Cellular dynamics in the muscle satellite cell niche.Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles.Current Translational Research and Murine Models For Duchenne Muscular Dystrophy."Mix of Mics"- Phenotypic and Biological Heterogeneity of "Multipotent" Muscle Interstitial Cells (MICs).Human iPSC-derived mesoangioblasts, like their tissue-derived counterparts, suppress T cell proliferation through IDO- and PGE-2-dependent pathways.Molecular scissors for in situ cellular repair.After GWAS: mice to the rescue?Satellite cell therapy - from mice to menRepair or replace? Exploiting novel gene and cell therapy strategies for muscular dystrophies.Ongoing therapeutic trials and outcome measures for Duchenne muscular dystrophy.Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology.
P2860
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P2860
Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Stem cell-mediated transfer of ...... meliorates muscular dystrophy.
@en
Stem cell-mediated transfer of ...... meliorates muscular dystrophy.
@nl
type
label
Stem cell-mediated transfer of ...... meliorates muscular dystrophy.
@en
Stem cell-mediated transfer of ...... meliorates muscular dystrophy.
@nl
prefLabel
Stem cell-mediated transfer of ...... meliorates muscular dystrophy.
@en
Stem cell-mediated transfer of ...... meliorates muscular dystrophy.
@nl
P2093
P50
P1476
Stem cell-mediated transfer of ...... ameliorates muscular dystrophy
@en
P2093
Hidetoshi Hoshiya
Libera Berghella
Mitsuo Oshimura
Roberto Bottinelli
Rossana Tonlorenzi
Sara Benedetti
Stefania Antonini
Yasuhiro Kazuki
P304
P356
10.1126/SCITRANSLMED.3002342
P407
P50
P577
2011-08-01T00:00:00Z