Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis.
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Targeting amino acid metabolism in cancer growth and anti-tumor immune responseDysregulated metabolism contributes to oncogenesisSerine, glycine and one-carbon units: cancer metabolism in full circleGenetically-defined metabolic reprogramming in cancerSmall Molecule Activation of PKM2 in Cancer Cells Induces Serine AuxotrophySerine is a natural ligand and allosteric activator of pyruvate kinase M2Structural basis of L-phosphoserine binding to Bacillus alcalophilus phosphoserine aminotransferasePLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cellsOncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells.Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generationFunctional genomics reveal that the serine synthesis pathway is essential in breast cancerPhosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesisIdentification of microRNAs inhibiting TGF-β-induced IL-11 production in bone metastatic breast cancer cells.Synergistic simvastatin and metformin combination chemotherapy for osseous metastatic castration-resistant prostate cancer.Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry.Analysis of gene expression during mineralization of cultured human periodontal ligament cellsBioinformatics analysis of the serine and glycine pathway in cancer cellsL-3-Phosphoserine phosphatase (PSPH) regulates cutaneous squamous cell carcinoma proliferation independent of L-serine biosynthesis.Positive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade.Integrated network analysis and logistic regression modeling identify stage-specific genes in Oral Squamous Cell CarcinomaSphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availabilityModeling cancer metabolism on a genome scale.Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.Cellular metabolism and disease: what do metabolic outliers teach us?Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.Resurgence of serine: an often neglected but indispensable amino AcidIncreased Expression of PHGDH and Prognostic Significance in Colorectal Cancer.Overexpression of the PSAT1 Gene in Nasopharyngeal Carcinoma Is an Indicator of Poor PrognosisThe importance of serine metabolism in cancerPhosphoglycerate dehydrogenase is a novel predictor for poor prognosis in gastric cancerThe histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation.High Expression of PHGDH Predicts Poor Prognosis in Non-Small Cell Lung CancerContribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cellsPrediction of therapeutic microRNA based on the human metabolic network.PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression.A world of sphingolipids and glycolipids in the brain--novel functions of simple lipids modified with glucose.Serine biosynthesis by photorespiratory and non-photorespiratory pathways: an interesting interplay with unknown regulatory networks.Mapping cancer cell metabolism with(13)C flux analysis: Recent progress and future challenges.Human metabolic network: reconstruction, simulation, and applications in systems biology.
P2860
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P2860
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Enhanced serine production by ...... stimulates osteoclastogenesis.
@en
Enhanced serine production by ...... stimulates osteoclastogenesis.
@nl
type
label
Enhanced serine production by ...... stimulates osteoclastogenesis.
@en
Enhanced serine production by ...... stimulates osteoclastogenesis.
@nl
prefLabel
Enhanced serine production by ...... stimulates osteoclastogenesis.
@en
Enhanced serine production by ...... stimulates osteoclastogenesis.
@nl
P2093
P50
P1476
Enhanced serine production by ...... stimulates osteoclastogenesis.
@en
P2093
Henri Sara
Henrik Edgren
Maija Wolf
Sanna-Maria Käkönen
Sirkku Pollari
P2888
P304
P356
10.1007/S10549-010-0848-5
P407
P577
2010-03-30T00:00:00Z