Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library

Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library

Item
http://www.wikidata.org/entity/Q39741643
Mechanism of Action and Initial, In Vitro SAR of an Inhibitor of the Shigella flexneri Virulence Regulator VirFNovel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.Identification of novel small molecule inhibitors of the XPA protein using in silico based screeningA fluorescence-based screen for ribosome binding antibiotics.Melting thermodynamics of reversible DNA/ligand complexes at interfaces.Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells.Xylopine Induces Oxidative Stress and Causes G2/M Phase Arrest, Triggering Caspase-Mediated Apoptosis by p53-Independent Pathway in HCT116 Cells.A novel ruthenium complex with xanthoxylin induces S-phase arrest and causes ERK1/2-mediated apoptosis in HepG2 cells through a p53-independent pathway.A ruthenium-based 5-fluorouracil complex with enhanced cytotoxicity and apoptosis induction action in HCT116 cells.Solid-phase synthesis of amidine-substituted phenylbenzimidazoles and incorporation of this DNA binding and recognition motif into amino acid and peptide conjugates.A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells
P2860

Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library

Item
http://www.wikidata.org/entity/Q39741643
description
2010 nî lūn-bûn
@nan
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-sg
2010年學術文章
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2010年學術文章
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2010年學術文章
@zh-hant
name
Semi-automated high-throughput ...... from a large compound library
@en
Semi-automated high-throughput ...... from a large compound library.
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type
label
Semi-automated high-throughput ...... from a large compound library
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Semi-automated high-throughput ...... from a large compound library.
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prefLabel
Semi-automated high-throughput ...... from a large compound library
@en
Semi-automated high-throughput ...... from a large compound library.
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Semi-automated high-throughput ...... from a large compound library
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P2093
P2860
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P31
P356
10.1016/J.BMCL.2010.01.033
P407
P433
P478
P50
P577
P5875
P698
P921
P932