Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells.
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Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complexAKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complexThe genetically encoded tool set for investigating cAMP: more than the sum of its partsStudying GPCR/cAMP pharmacology from the perspective of cellular structureFRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cellsPhosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterasesA plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors.Regulation by Ca2+-signaling pathways of adenylyl cyclases.β-Adrenergic cAMP signals are predominantly regulated by phosphodiesterase type 4 in cultured adult rat aortic smooth muscle cellsPDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblastsAn improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.Interventricular differences in β-adrenergic responses in the canine heart: role of phosphodiesterases.Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMPRole of membrane microdomains in compartmentation of cAMP signaling.Reporting from the field: genetically encoded fluorescent reporters uncover signaling dynamics in living biological systems.Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source.The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.Pharmacological distinction between soluble and transmembrane adenylyl cyclases.Novel cAMP signalling paradigms: therapeutic implications for airway diseaseOrganization of cAMP signalling microdomains for optimal regulation by Ca2+ entry.The primary cilium as a novel extracellular sensor in boneBiophysical techniques for detection of cAMP and cGMP in living cells.Decoding spatial and temporal features of neuronal cAMP/PKA signaling with FRET biosensors.cAMP signaling in subcellular compartments.Adenylate cyclase-centred microdomains.cAMP signaling microdomains and their observation by optical methods.Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief.Direct demonstration of discrete Ca2+ microdomains associated with different isoforms of adenylyl cyclase.Role of phosphodiesterase and adenylate cyclase isozymes in murine colonic glucagon-like peptide 1 secreting cells.Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu.TRPC1 contributes to the Ca2+-dependent regulation of adenylate cyclases.cAMP measurements with FRET-based sensors in excitable cells.Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β2AR-cAMP Responsiveness in Murine Hearts.[Physiopathology of cAMP/PKA signaling in neurons].Real-time examination of cAMP activity at relaxin family peptide receptors using a BRET-based biosensor
P2860
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P2860
Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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name
Distinct pools of cAMP centre ...... pituitary-derived GH3B6 cells.
@en
Distinct pools of cAMP centre ...... pituitary-derived GH3B6 cells.
@nl
type
label
Distinct pools of cAMP centre ...... pituitary-derived GH3B6 cells.
@en
Distinct pools of cAMP centre ...... pituitary-derived GH3B6 cells.
@nl
prefLabel
Distinct pools of cAMP centre ...... pituitary-derived GH3B6 cells.
@en
Distinct pools of cAMP centre ...... pituitary-derived GH3B6 cells.
@nl
P2093
P2860
P356
P1476
Distinct pools of cAMP centre ...... pituitary-derived GH3B6 cells
@en
P2093
Antonio Ciruela
Dermot M F Cooper
Laura-Jo Ayling
Nanako Masada
Sebastian Wachten
Viacheslav O Nikolaev
P2860
P304
P356
10.1242/JCS.058594
P407
P577
2010-01-01T00:00:00Z