Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition. - Test2 - elhamkhani - TriplyDB

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

http://www.wikidata.org/entity/Q39780644

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Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor Hypoxia Epigenomics of leukemia: from mechanisms to therapeutic applications Dedifferentiation and reprogramming: origins of cancer stem cells Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention Alterations in chromatin are associated with increases in collagen III expression in aging nephropathy Epigenetic regulation of epithelial-mesenchymal transition Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression General approach to epipolythiodiketopiperazine alkaloids: total synthesis of (+)-chaetocins A and C and (+)-12,12'-dideoxychetracin A Small-molecular modulators of cancer-associated epigenetic mechanisms.BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production.Targeting protein lysine methylation and demethylation in cancers.Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer.Tricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity.The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells.Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns.Improved therapeutic effect against leukemia by a combination of the histone methyltransferase inhibitor chaetocin and the histone deacetylase inhibitor trichostatin A.Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells.Epigenetic reprogramming in cancer.Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesis Epigenetics in cancer stem cells.NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia.Heterochromatin dysregulation in human diseases.Histone methylation in myelodysplastic syndromes.Global epigenetic profiling in bladder cancer.Promises and challenges of anticancer drugs that target the epigenome.Drugging the undruggable: transcription therapy for cancer.The mechanistic role of DNA methylation in myeloid leukemogenesis.SUV39H1 mediated SIRT1 trans-repression contributes to cardiac ischemia-reperfusion injury.Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation.SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation.Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1.Histone lysine methyltransferase, suppressor of variegation 3-9 homolog 1, promotes hepatocellular carcinoma progression and is negatively regulated by microRNA-125b.High expressions of histone methylation- and phosphorylation-related proteins are associated with prognosis of oral squamous cell carcinoma in male population of Taiwan.Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs.Histone lysine methyltransferase SUV39H1 is a potent target for epigenetic therapy of hepatocellular carcinoma.

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P2860

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

http://www.wikidata.org/entity/Q39780644

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

@en

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

@nl

type

label

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

@en

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

@nl

prefLabel

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

@en

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

@nl

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P1476

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

@en

P2093

A Lakshmikuttyamma

http://www.w3.org/2001/XMLSchema#string

C R Geyer

http://www.w3.org/2001/XMLSchema#string

J F DeCoteau

http://www.w3.org/2001/XMLSchema#string

S A Scott

http://www.w3.org/2001/XMLSchema#string

P2860

DNA methylation patterns and epigenetic memory

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

SUV39H1 interacts with HTLV-1 Tax and abrogates Tax transactivation of HTLV-1 LTR.

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

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576-588

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10.1038/ONC.2009.361

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4

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1024540877

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19881540

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