Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. - Test2 - elhamkhani - TriplyDB

Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.

Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.

http://www.wikidata.org/entity/Q39825334

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Posttranscriptional Regulation of Splicing Factor SRSF1 and Its Role in Cancer Cell Biology Connecting the speckles: Splicing kinases and their role in tumorigenesis and treatment response Molecular mechanisms of epithelial-mesenchymal transition Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma.The RNAissance family: SR proteins as multifaceted regulators of gene expression Chemical treatment enhances skipping of a mutated exon in the dystrophin gene.Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinoma Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues.Crosstalk between Wnt Signaling and RNA Processing in Colorectal Cancer.Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer.Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells.Alternative pre-mRNA splicing in digestive tract malignancy.Making alternative splicing decisions during epithelial-to-mesenchymal transition (EMT).Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT).Regulation of splicing by SR proteins and SR protein-specific kinases.Hallmarks of alternative splicing in cancer.Epithelial-mesenchymal transition is regulated at post-transcriptional levels by transforming growth factor-β signaling during tumor progression.Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways.Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms.Cardiac glycosides correct aberrant splicing of IKBKAP-encoded mRNA in familial dysautonomia derived cells by suppressing expression of SRSF3.Insufficient ability of Rac1b to perturb cystogenesis.WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway.Osteopontin-c isoform levels are associated with SR and hnRNP differential expression in ovarian cancer cell lines.Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.Both sides of the same coin: Rac1 splicing regulating by EGF signaling.Signaling Pathways Driving Aberrant Splicing in Cancer Cells.SRSF3 recruits DROSHA to the basal junction of primary microRNAs.Alternative splicing within the Wnt signaling pathway: role in cancer development.Multitasking β-catenin: from adhesion and transcription to RNA regulation

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P2860

Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.

http://www.wikidata.org/entity/Q39825334

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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name

Antagonistic SR proteins regul ...... e PI3-kinase and Wnt pathways.

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Antagonistic SR proteins regul ...... e PI3-kinase and Wnt pathways.

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type

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Antagonistic SR proteins regul ...... e PI3-kinase and Wnt pathways.

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Antagonistic SR proteins regul ...... e PI3-kinase and Wnt pathways.

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prefLabel

Antagonistic SR proteins regul ...... e PI3-kinase and Wnt pathways.

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Antagonistic SR proteins regul ...... e PI3-kinase and Wnt pathways.

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Human Molecular Genetics

P1476

Antagonistic SR proteins regul ...... he PI3-kinase and Wnt pathways

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P2093

Paulo Matos

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Peter Jordan

http://www.w3.org/2001/XMLSchema#string

Vânia Gonçalves

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P2860

The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

ASD: a bioinformatics resource on alternative splicing.

Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase

Rho GTPases: biochemistry and biology

Wnt/beta-catenin signaling in development and disease

Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA

Regulation of apoptosis by alternative pre-mRNA splicing

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3696-3707

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scholarly article

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10.1093/HMG/DDP317

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19

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18

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Vânia Gonçalves

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2009-07-13T00:00:00Z

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26671091

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19602482

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